European Journal of Cardio-Thoracic Surgery, Vol 1, 29-32, Copyright © 1987 by European Association for Cardio-thoracic Surgery
Barrett's esophagus and adenocarcinoma
M Ribet, E Mensier and FR Pruvot
Surgical Clinic, Albert Calmette Hospital, Lille, France.
Sixty-two cases of Barrett's esophagus were observed among 707 patients
with hiatal hernia (8.7%). The symptomatology of this condition is
described. An additional 10 adenocarcinomas were associated with a
Barrett's esophagus--a carcinoma prevalence of 13.8%. Differences in
pathology and clinical manifestations of nonmalignant and malignant cases
were determined. Fifty-one patients with nonmalignant Barrett's esophagus
were operated upon conservatively, while 11 underwent resection. Our
results favor conservative surgery via an abdominal approach. The patients
with adenocarcinomas underwent esophageal resection with six apparent cures
from 6 months to 5 years. Histological study showed specialized epithelium
in 8 of 10 cases and severe dysplasia in 5. Our clinical study of Barrett's
esophagus shows an incidence of malignancy equal to 1 new case per 274
patient-years (1.72%). It is still not firmly established whether
correction of reflux will influence the level of columnar epithelium in the
esophagus, esophageal dysplasia, and the risk of malignancy.