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European Journal of Cardio-Thoracic Surgery, Vol 10, 996-1001, Copyright © 1996 by European Association for Cardio-thoracic Surgery
LK von Segesser, M Genoni, A Kunzli, M Lachat, U Niederhauser, P Vogt, M Schonbeck and M Turina
OBJECTIVE: To assess the outcome of patients with ruptured descending
thoracic and thoracoabdominal aortic aneurysms undergoing emergency repair,
in comparison to elective surgery for chronic lesions. METHODS: A
prospective study of 100 consecutive patients operated upon the descending
aorta (1-8 segments) using proximal unloading and distal protection with
partial cardiopulmonary bypass, heparin surface-coated perfusion equipment
and low systemic heparinization (loading dose 100 IU/kg, activated
coagulation time > 180 s), staged cross-clamping, sealed grafts and
graft inclusion. RESULTS: Arteriosclerotic lesions were present in 53/100
patients (53%) for all, 30/53 (56%) for chronic, and 21/33 (63%) for
ruptured, aneurysms (NS). Dissecting lesions were found in 38/100 patients
(38%) for all, 20/53 (38%) for chronic, and 8/33 (24%) for ruptured
aneurysms (NS). Preoperative hematocrit was 38 +/- 6% for all, 40 +/- 5%
for chronic, and 33 +/- 5% for ruptured aneurysmal patients (P < 0.001
ruptured versus chronic). The extent of aortic repair (1-8 segments) was
3.3 +/- 1.6 for all, 3.5 +/- 1.5 for chronic, and 3.2 +/- 1.4 for ruptured,
aneurysms (NS). Transdiaphragmatic repair was performed in 51/100 (51%) of
all, 28/53 (53%) of chronic, and 17/33 (51%) of ruptured aneurysms (NS).
Aortic cross-clamp time was 38 +/- 21 min for all, 39 +/- 24 min for
chronic, and 38 +/- 17 min for ruptured, aneurysmal patients (NS). The
amount of red cells washed and autotransfused was 2792 +/- 2239 ml in all,
3143 +/- 2531 ml in chronic, and 2074 +/- 1350 ml in ruptured, aneurysmal
patients (P < 0.025). The amount of packed red cells required was 2181
+/- 1830 ml for all, 1736 +/- 1333 ml for chronic, and 2947 +/- 2395 ml for
ruptured aneurysmal patients (P < 0.010). Thirty-day mortality was 9/100
(9%) for all, 3/53 (6%) for chronic, and 5/33 (15%) for ruptured aneurysmal
patients (NS). Parapareses/plegias occurred in 9/100 (9%) of all, 6/53
(11%) of chronic, and 3/33 (9%) of ruptured, aneurysmal patients (NS).
Stepwise regression analysis identified aortic cross- clamp time as a
predictor of early mortality (P = 0.002) and parapareses and paraplegias (P
= 0.001). Age (P = 0.001), extent of repair (P = 0.008) and preoperative
hematocrit (P = 0.001) were predictors for homologous transfusion
requirements. CONCLUSION: Emergency repair of ruptured descending thoracic
and thoracoabdominal aortic aneurysms can be achieved with acceptable
results.
ARTICLES
Surgery for ruptured thoracic and thoraco-abdominal aortic aneurysms
Clinic for Cardiovascular Surgery CH-1011 Lausanne, Switzerland.
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