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European Journal of Cardio-Thoracic Surgery, Vol 10, 722-726, Copyright © 1996 by European Association for Cardio-thoracic Surgery
DA Sharpe, K Dixon and K Moghissi
OBJECTIVE: To evaluate the efficacy of endoscopic laser treatment (ELT) in
patients with endoluminal tracheal obstruction. METHOD: A neodymium:
yttrium aluminium, garnet (Nd:YAG) laser was used on 60 patients with
significant (> 50%) tracheal stenosis. They were grouped as follows:
primary tracheal malignancy (PTM n = 11), secondary tracheal malignancy
(STM n = 27), benign tracheal tumours (BTT n = 4) and inflammatory tracheal
stenosis (ITS n = 18). Assessment was made clinically, endoscopically and
using ventilatory function tests (forced vital capacity (FVC) and peak
expiratory flow rate (PEFR)), before and after treatment. RESULTS: There
was no treatment-related mortality. Peak expiratory flow rate improved
significantly overall and in the PTM, STM and ITS groups. There was no
significant improvement in FVC overall or in any of the individual groups.
Subjectively, 98% of the patients felt improved by ELT. The survival in
each group was: in the PTM group three patients are alive at 36, 49 and 74
months while all other patients died, giving a mean survival of 8.8 +/- 2.6
months. In the STM group the mean survival was 4.7 +/- 4.2 months. In the
BTT group all patients are alive at the time of writing, two require
regular ELT. In the ITS group three patients died, two required Montgomery
tracheostomy tubes for tracheomalacia, seven are receiving regular ELT and
six are disease free at the time of writing. CONCLUSION: We conclude that
ELT is an effective method for the palliation of malignancy which
occasionally gives long-term survival. It has a place in the management of
benign tracheal neoplasia and inflammatory stenosis with a potential for
cure in these cases.
ARTICLES
Endoscopic laser treatment for tracheal obstruction
Humberside Cardiothoracic Centre, Castle Hill Hospital, Cottingham, UK.
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