European Journal of Cardio-Thoracic Surgery, Vol 11, 769-773, Copyright © 1997 by European Association for Cardio-thoracic Surgery
Phosphatidylcholine coated chest drains: are they better than conventional drains after open heart surgery?
P Kumar, D McKee, M Grant and J Pepper
INTRODUCTION: Inadequate thoracic drainage after open heart surgery has
serious deleterious consequences. Thrombus formation within the chest
drains is primarily responsible for the occlusion of chest drains. Chest
drains coated with derivatives of phosphatidylcholine (PC), commonest
phospholipid on cell membranes, potentially have a less thrombogenic
surface. MATERIALS AND METHODS: In a prospective randomised double blind
study, we compared PC-coated drains (Group I, n = 25) with non coated
drains (Group II, n = 26) after open heart surgery. Drain performance,
post-operative complications and clinical course were compared. RESULTS:
PC-coated drains had a significantly shorter period of drainage, 20.4 +/-
1.0 versus 28.9 +/- 3.7 h (P < 0.05). Otherwise, mean volume drained,
number clots removed from drain and the ease of drainage of the two types
of drains were similar. There were no significant differences in the
incidence of post-operative pericardial effusions, dysrhythmias, ambulation
time and hospital stay. CONCLUSIONS: We conclude that the PC coated drains
may be of importance in cases where prolonged drainage is anticipated
otherwise they have no significant advantage.