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European Journal of Cardio-Thoracic Surgery, Vol 11, 1154-1157, Copyright © 1997 by European Association for Cardio-thoracic Surgery
IM Ali, AA Sanalla and V Clark
OBJECTIVES: To determine whether restarting of Beta Blocker following
cardiac surgery would reduce the incidence and the severity of post-
operative atrial fibrillation (AF). METHODS: 210 patients who underwent
elective coronary artery bypass grafting were randomized to control (C) (n
= 105) and Beta Blockers (BB) (n = 105) groups. Preoperatively all patients
were on one type or another of betablockers. Postoperatively only the (BB)
group received the medication. Both groups were well matched and had the
same cardioplegic technique. RESULTS: It was found that; (1) post op (AF)
developed in 40 patients of group (C) and in 18 patients of group (BB) P
value < 0.02. (2) 73% of (AF) patients in group (C) and 81% in group
(BB) were older than 70 years of age. (3) 76% of the (AF) in (BB) group
versus 43% in (C) group were converted to sinus rhythm or to a stable
controlled rhythm within 24 h or less. P value < 0.01. CONCLUSIONS: The
results indicate that restarting the Beta Blockers in the post-operative
period after coronary bypass grafts significantly control the incidence and
the severity of atrial fibrillation. Also it confirms the strong relation
between the older age and (AF) occurrence.
ARTICLES
Beta-blocker effects on postoperative atrial fibrillation
Department of Surgery, Dalhousie University, Victoria General Hospital, Halifax, N.S., Canada.
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