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European Journal of Cardio-Thoracic Surgery, Vol 12, 304-311, Copyright © 1997 by European Association for Cardio-thoracic Surgery
G Brandrup-Wognsen, H Berggren, K Caidahl, T Karlsson, H Sjoland and J Herlitz
OBJECTIVE: To describe the impact of coronary artery bypass grafting on
chest pain during 2 years of follow-up after the operation and to identify
predictors of chest pain and its relationship to myocardial ischaemia 2
years after the operation. METHODS: Patients were approached with a
questionnaire at the time of coronary angiography (1291) and 3 months
(1664), 1 year (1638) and 2 years (1613) after coronary artery bypass
grafting. Two years after the operation, a computerised 12-lead
electrocardiogram was obtained during a standardised bicycle exercise test
(618). RESULTS: Prior to surgery, 37% of the patients were unable to
perform physical activity compared with 6% after the operation (P <
0.0001 for change in degree of limitation). Only 3% had no chest pain at
all prior to the operation, while 58% of the patients were free from chest
pain 2 years after surgery (P < 0.0001). We found no correlation between
patients reporting chest pain and signs of ischaemia at exercise test, but
there was a highly significant correlation with chest pain during the
exercise test (P < 0.0001). Independent predictors of chest pain were
severity of preoperative angina (P < 0.0001), younger age (P = 0.0009),
previous coronary artery bypass grafting (P = 0.003), duration of symptoms
(P = 0.005), the need for prolonged cardiopulmonary bypass (P = 0.04) and
the absence of left main stenosis (P = 0.04). CONCLUSION: Independent
predictors of chest pain were identified 2 years after coronary artery
bypass grafting. There was a dramatic improvement after coronary artery
bypass grafting. However, almost half the patients complained of some kind
of chest pain even after the operation. This chest pain correlated well
with chest pain during the exercise test but not with signs of myocardial
ischaemia.
ARTICLES
Predictors for recurrent chest pain and relationship to myocardial ischaemia during long-term follow-up after coronary artery bypass grafting
Division of Thoracic and Cardiovascular Surgery, Sahlgrenska University Hospital, Goteborg, Sweden.
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