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European Journal of Cardio-Thoracic Surgery, Vol 12, 460-465, Copyright © 1997 by European Association for Cardio-thoracic Surgery
V Alexi-Meskishvili, R Hetzer, I Dahnert, Y Weng and PE Lange
OBJECTIVE: The objective of this study was to determine causes of severe
left atrioventricular (AV) incompetence and the factors leading to the
success of valve repair later after correction of atrioventricular septal
defects (AVSD). METHODS: A total of 28 patients aged 5 months to 38 years
(mean age 6.7 years) were operated for significant (grade II-III) left AV
valve incompetence (LAVVI), two months to twenty-five years (median 1.5
years) after correction of complete (11 patients) or partial
atrioventricular septal defects. Fourteen patients had initially undergone
surgery during infancy. RESULTS: At reoperation a completely open or
partially sutured cleft was found in 16 patients combined with dysplastic
valve tissue in four cases, with a fibrotic valve in three cases, with
posterior leaflet prolapse in two cases, with a double orifice valve in
three cases, and a parachute valve in two cases. Partial or complete
reopening of a previously sutured cleft caused by suture dehiscence was
found in 12 cases combined with a fibrotic valve in five cases, with a
dysplastic valve in one case and with severe deformity of valve in one
case. A combination of these anomalies was observed in seven patients in
both groups. Left atrioventricular valve repair including cleft closure
combined with annuloplasty and other surgical procedures resulted in the
disappearance or significant diminishing of LAVI in 18 patients (64%).
Severe SAVI persisted in six patients, five of them exhibiting a
combination of several additional left AV valve anomalies (fibrotic or
dysplastic valve, parachute valve). Five of these six patients underwent
successful left AV valve replacement with a mechanical prosthesis 7 days to
2 years after reoperation. The presence of additional left AV valve
anomalies was the single statistically significant factor for recurrent
major LAVVI after reoperation (P = 0.0106). There were two postoperative
deaths in patients with mild LAVVI after surgery, and no late deaths.
CONCLUSION: An open cleft is the major factor of late severe SAVVI after
correction of AVSD. Although suturing the cleft in conjunction with
performing annuloplasty improved valvular function in most of the cases,
the presence of severe left AV valve anomalies increased the risk of
recurrent LAVVI and the need for valve replacement, thus playing a major
role in determining the outcome of valve reconstruction in patients after
reoperation.
ARTICLES
Results of left atrioventricular valve reconstruction after previous correction of atrioventricular septal defects
Department of Thoracic and Cardiovascular Surgery, German Heart Institute, Berlin, Germany.
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