| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
European Journal of Cardio-Thoracic Surgery, Vol 12, 730-737, Copyright © 1997 by European Association for Cardio-thoracic Surgery
C Basso, M Valente, A Poletti, D Casarotto and G Thiene
OBJECTIVE: Retrospective study of surgical pathology experience on cardiac
and pericardial tumors at the University of Padua in the era of
immunohistochemistry and endomyocardial biopsy. METHODS: In the period
1970-1995, we studied 125 bioptic primary neoplasms: specimens were
obtained from surgical resection in 116 cases, heart transplantation in 3,
pericardiectomy in 3, endomyocardial biopsy in 2 and thoracoscopic biopsy
in 1. Tumor histotype was established by light microscopy and more recently
by immuno-histochemistry, using a large panel of antibodies, through
avidin-biotin peroxidase method, against factor VIII-related antigen,
ulex-europaeus, desmin, myoglobin, muscle- specific actin, smooth
muscle-specific actin, vimentin, cytokeratins, leukocytic common antigen,
neurofilaments and S100-protein. RESULTS: One hundred and thirteen were
benign neoplasms: myxoma was the most frequent (87 cases) followed by
pericardial cyst (8), endocardial papilloma (5), fibroma (3), rhabdomyoma
(3), hematic cyst (2), teratoma (2), hemangioma (1), celothelioma (1) and
lipoma (1). Malignancy was diagnosed in 12 cases, and consisted of
pericardial mesothelioma (3), myxosarcoma (3), angiosarcoma (2),
fibrosarcoma (2) and leiomyosarcoma (2); 4 of them were intracavitary
atrial masses and were supposed to be atrial myxoma on the clinical ground.
Differential diagnosis included endocardial thrombosis (10), metastasis of
concealed extracardiac tumors (5), echinococcosis (3), and Loeffler's
fibroplastic endocarditis (3). In 4 cases, cardiac mass histotype was
defined without thoracotomy, through endomyocardial (3) and thoracoscopic
(1) biopsy. CONCLUSIONS: A large spectrum of cardiac tumors is observed in
the surgical pathology practice. Although the diagnosis of cardiac masses
is easily attainable by routine imaging techniques, differential diagnosis
between primary and secondary tumors, malignant and benign forms, and non
neoplastic masses, is achievable only by a thorough microscopic study of
surgical resections. The role of the cardiac pathologist is becoming
crucial as in other fields of oncology.
ARTICLES
Surgical pathology of primary cardiac and pericardial tumors
Department of Pathology, University of Padua Medical School, Italy.
This article has been cited by other articles:
|
|
 |
|
  M. C. Speltz, J. C. Manivel, A. H. Tobias, and D. W. Hayden Primary Cardiac Fibrosarcoma with Pulmonary Metastasis in a Labrador Retriever Vet. Pathol., May 1, 2007; 44(3): 403 - 407. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Mazzola, J.-P. Spano, M. Valente, R. Gregorini, C. Villani, M. D. Eusanio, M. Ciocca, U. Minuti, R. Giancola, C. Basso, et al. Leiomyosarcoma of the left atrium mimicking a left atrial myxoma J. Thorac. Cardiovasc. Surg., January 1, 2006; 131(1): 224 - 226. [Full Text] [PDF]
|
|
|
|
|
|
M. A. Padalino, C. Basso, O. Milanesi, V. L. Vida, G. S. Moreolo, G. Thiene, and G. Stellin Surgically treated primary cardiac tumors in early infancy and childhood J. Thorac. Cardiovasc. Surg., June 1, 2005; 129(6): 1358 - 1363. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Weinrich, H. F. Lausberg, S. Pahl, and H.-J. Schafers A Bronchogenic Cyst of the Right Ventricular Endocardium Ann. Thorac. Surg., February 1, 2005; 79(2): e13 - e14. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C Basso, T Bottio, M Valente, R Bonato, D Casarotto, and G Thiene Primary cardiac valve tumours Heart, October 1, 2003; 89(10): 1259 - 1260. [Full Text] [PDF]
|
|
|
|
 |
|
 N. Sadeghi, S. Sadeghi, and A. Karimi Mitral valve recurrence of a left atrial myxoma Eur. J. Cardiothorac. Surg., March 1, 2002; 21(3): 568 - 573. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Kutsal, S. Tansal, H. Okutan, and I. Tuncer Primary malignant mesenchymoma of the heart Eur. J. Cardiothorac. Surg., January 1, 2002; 21(1): 124 - 126. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Patane, E. Zingarelli, A. Verzini, and M. di Summa Vascular complications associated with a large cardiac fibroma Eur. J. Cardiothorac. Surg., September 1, 2001; 20(3): 636 - 638. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. S. Hu, C. C. Sun, and Z. Zheng Heart Leiomyosarcoma Mimicking Pulmonary Thromboembolism Asian Cardiovasc Thorac Ann, March 1, 2001; 9(1): 68 - 70. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Testolin, C. Basso, D. Pittarello, D. Casarotto, and M. Valente Cardiogenic shock due to metastatic cardiac lymphoma: still a diagnostic and therapeutic challenge Eur. J. Cardiothorac. Surg., March 1, 2001; 19(3): 365 - 368. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Kipfer, L. Englberger, E. Stauffer, and T. Carrel Rare presentation of cardiac hemangiomas Ann. Thorac. Surg., September 1, 2000; 70(3): 977 - 979. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. A. Araoz, S. L. Mulvagh, H. D. Tazelaar, P. R. Julsrud, and J. F. Breen CT and MR Imaging of Benign Primary Cardiac Neoplasms with Echocardiographic Correlation RadioGraphics, September 1, 2000; 20(5): 1303 - 1319. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. G. Di Mattia, A. Assaghi, A. Mangini, S. Ravagnan, S. Bonetto, and P. Fundaro Mitral valve repair for anterior leaflet papillary fibroelastoma: two case descriptions and a literature review Eur. J. Cardiothorac. Surg., January 1, 1999; 15(1): 103 - 107. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Kornberg, S.M. Wildhirt, E. Kreuzer, and B. Reichart Asymptomatic right atrial leiomyosarcoma with tricuspid valve obstruction in a young female patient Eur. J. Cardiothorac. Surg., December 1, 1998; 14(6): 635 - 638. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
