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Eur J Cardiothorac Surg 1999;15:433-437
© 1999 Elsevier Science NL


Time trend in the surgical management of patients with lung carcinoma1

Marc de Perrota, Marc Lickerb, John Roberta, Anastase Spiliopoulosa

a Unit of Thoracic Surgery, University Hospital of Geneva, Geneva, Switzerland
b Division of Anesthesiology, University Hospital of Geneva, Geneva, Switzerland

Received 21 September 1998; received in revised form 21 December 1998; accepted 12 January 1999.

Corresponding author. Department of Surgery, University Hospital of Geneva, rue Micheli-du-Crest 24, 1211 Geneva 14, Switzerland. Tel.: +41-22-372-7873; fax: +41-22-372-7880.

Objective: The goal of the study was to analyze the histological and clinical trends in lung carcinoma and their influence upon the preoperative evaluation, surgical procedures and survival. Methods: We retrospectively reviewed the charts of 1079 consecutive patients who underwent surgery for primary lung carcinoma between 1977 and 1996 in our institution. Patients were divided into five equal 4-year periods according to the year of surgery (1977–1980; 1981–1984; 1985–1988; 1989–1992; 1993–1996). Results: Between 1977–1980 and 1993–1996, the incidence of squamous cell carcinoma significantly declined, whereas the incidence of adenocarcinoma and bronchioloalveolar carcinoma increased. During the same period, the proportion of squamous cell carcinoma visualized at bronchoscopy and the rate of preoperative histological diagnosis significantly decreased. An increasing proportion of lobectomy and less extended resection was associated with an increasing number of patients with stage I carcinoma. Meanwhile, the operative mortality significantly declined from 9 to 4% and the 5-year survival improved from 25 up to 40%. Conclusion: Over the last two decades, the shift in histological distribution was associated with an increasing proportion of patients with stage I disease, a lower operative mortality and a better 5-year survival.

Key Words: Lung carcinoma • Operative mortality • Survival • Time trend




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