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Eur J Cardiothorac Surg 1999;16:471-474
© 1999 Elsevier Science NL

Case report

Bronchial arterial infusion with cisplatin followed by irradiation successfully treats recurrent stage IVb thymic large cell carcinoma

Shizuka Kasedaa, Kunihiko Shimizub, Takashi Yamanec, Hitoshi Sugiurad

a Department of Thoracic Surgery, Saiseikai Kanagawa-ken Hospital, Yokohama 221-8601, Japan
b Department of Internal Medicine, Saiseikai Kanagawa-ken Hospital, Yokohama 221-8601, Japan
c Radiology, Saiseikai Kanagawa-ken Hospital, Yokohama 221-8601, Japan
d Department of Pathology, Clinical Research Laboratories, Kawasaki Municipal Kawasaki Hospital, Kawasaki 210-0013, Japan

Corresponding author. Tel.: +81-45-432-1111; fax: +81-45-432-1119
e-mail: kaseda{at}ra2.so-net.ne.jp

A 48-year-old female was treated with three courses of chemotherapy combined with bronchial arterial infusion (BAI) with cisplatin and intravenous drip infusion with bleomycin and vinblastine for a recurrent thymic large cell carcinoma seen 1 year after the initial operation. The patient had subsequently undergone irradiation. No sign of recurrence has been noted with a follow-up period of 6 years after the initial operation. This is the first reported case of survival from recurrence of thymic large cell carcinoma. BAI combined with irradiation should be considered as one of the treatments of choice in a recurrence like we present herein.

Key Words: Thymus • Thymic carcinoma • Large cell carcinoma • Bronchial artery • Chemotherapy • Irradiation






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Copyright © 1999 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.