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Eur J Cardiothorac Surg 2000;17:631-636
© 2000 Elsevier Science NL

Tetralogy of Fallot: what operation, at which age

Cardiac Unit, Royal Liverpool Children's Hospital, AlderHey, Eaton Road, Liverpool L12 2AP, Liverpool, UK

Corresponding author. Tel.: +44-151-252-5635; fax: +44-151-252-5643
e-mail: mpozzi{at}liverpedcard.u-net.com

Background: The optimal management of tetralogy of Fallot is still under debate, particularly with respect to surgical approach and the age of operation. In recent times a transatrial-transpulmonary approach and primary repair in younger patients is favoured. The purpose of the present study was to analyze the result of our current surgical management by assessing the perioperative and intermediate term follow up in order to define the optimal strategy and timing of operation for our institution. Methods: One hundred and thirty two patients with tetralogy of Fallot who underwent definitive repair between May 1993 and December 1998 were analyzed by reviewing their medical records and follow-up. Median age was 15.5 (2.3–68.6) months and median weight was 8.8 (5–16) kg. Ten (7.57%) patients were under 6 months, 38 (28.78%) were between 6 and 12 months, 36 (27.27%) were between 12 and 18 months, 23 (17.42%) were between 18 and 24 months and 25 (18.93%) were more than 24 months age. During the study period there was a move to earlier surgery and differing methods of repair depending on the anatomy observed. Follow up was conducted by the referring cardiologist. Median follow up was 35.48 (8.07–74.93) months. Results: Forty-two (31.8%) patients required a palliative procedure before total correction due to unfavourable anatomy. Subpulmonary infundibular obstruction with a fibrous component increased significantly with age (P<0.05). Operations were entirely transatrial in 14 (10.6%), transatrial and transpulmonary in 69 (52.2%), transatrial and transventricularly in 42 (31.8%) and a homograft conduit was used in seven (5.3%) patients. Younger patients had narrower pulmonary valves and required a transannular patch more frequently. All patients were in sinus rhythm, 28 (21.1%) showing right bundle branch block. Median hospital stay was 8 (5–54) days. No patient required reintervention during follow up and there was no early or late mortality. Conclusion: Correction of tetralogy of Fallot at younger age does not increase morbidity or mortality and has potential advantages. A surgical technique adapted to the anatomy of the right ventricular outflow tract, achieves the best results.

Key Words: Tetralogy of Fallot • Young age • Surgical approach • Anatomical

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