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Eur J Cardiothorac Surg 2002;21:149-151
© 2002 Elsevier Science NL


Case report

Difficulties in diagnosis and treatment of ectopic ACTH-producing tumors of the chest

Chiara Dall'Astaa, Luigi Santambrogiob, Massimo Castellanic, Bruno Ambrosia*

a Institute of Endocrine Sciences, University of Milan, Ospedale Maggiore IRCCS – pad. Granelli Via F. Sforza 35, 20122 Milan, Italy
b Unit of Thoracic Surgery, University of Milan, Ospedale Maggiore IRCCS – pad. Monteggia Via F. Sforza 35, 20122 Milan, Italy
c Department of Nuclear Medicine, University of Milan, Ospedale Maggiore IRCCS – pad. Granelli Via F. Sforza 35, 20122 Milan, Italy

Received 18 July 2001; received in revised form 15 October 2001; accepted 18 October 2001.

* Corresponding author. Instituto Policlinico San Donato, Divisione di Endocrinologia e Diabetologia, via Morandi 30, 20097 San Donato Milanese, Milano, Italy. Tel./fax: +39-02-52774-444
e-mail: bruno.ambrosi{at}unimi.it

It is widely accepted that surgery is the first choice treatment for ACTH-secreting tumors, most of them being lung or bronchial tumors. However, the localization of such lesions is rather difficult and it needs a compelling work-up. Here we present the results of different hormonal and imaging investigations and the surgical outcome of three patients with ectopic Cushing's syndrome.

Key Words: Ectopic Cushing's syndrome • 111In-pentetreotide scintigraphy • 18F-fluorodeoxyglucose positron emission tomography • Pulmonary lobectomy • Thoracic surgery




This article has been cited by other articles:


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Eur. J. Cardiothorac. Surg.Home page
P. L. Filosso, O. Rena, E. Ruffini, and A. Oliaro
Ectopic ACTH-producing tumors of the chest and octreotide scintigraphy
Eur. J. Cardiothorac. Surg., June 1, 2002; 21(6): 1126 - 1126.
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Copyright © 2002 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.