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Eur J Cardiothorac Surg 2003;23:728-734
© 2003 Elsevier Science NL
Department of Paediatric Cardiac Surgery, Collegium Medicum, Jagiellonian University, 265 Wielicka St., 30-663 Cracow, Poland
Received 1 October 2002; received in revised form 20 January 2003; accepted 23 January 2003.
* Corresponding author. Tel.: +48-12-568-1023; fax: +48-12-657-3947
e-mail: mimalec{at}cyf-kr.edu.pl
Objective: The aim of this study was to assess changes in early and late haemodynamic status after the Norwood procedure (NP), caused by the implementation of right ventricle-to-pulmonary artery shunt (RV-PA). Methods: A consecutive series of 68 children with hypoplastic left heart syndrome underwent NP: Group 1 (n=31) with the application of a modified Blalock-Taussig shunt and Group 2 (n=37) with RV-PA. Haemodynamic data from the early postoperative period (72 h after the operation) and cardiac catheterisation data, as well as blood tests before the hemi-Fontan procedure (HF) were analysed. Univariate (
2 test, MannWhitney's and Student's t-tests) and multiple regression analysis were carried out. Results: In Group 1, circulatory collapse requiring resuscitation occurred in 15 (48.4%) children, within 72 h after the procedure. The resuscitation was unsuccessful in nine (29%) cases. The operative mortality (30 days) was 35%. In Group 2, two (5%) children died within the early and two (5%) within the late postoperative period. The postoperative course in the remaining children from Group 2 was uneventful. In Group 2 there was a significantly higher mean diastolic pressure after NP (P<0.05). The arterial pulse pressure after NP was significantly lower in Group 2 (P<0.05). Before HF, the application of RV-PA was associated with a lower Qp:Qs ratio (P=0.020), lower aortic pulse pressure (P=0.004) and lower aortic oxygen saturation (P=0.039). Conclusions: A stable haemodynamic status due to independent coronary perfusion, higher diastolic and lower pulse pressure is the most advantageous effect of RV-PA, resulting in a lower mortality and morbidity after NP. A lower Qp:Qs ratio eliminates the danger of the ventricular volume overload and ensures good conditions for the development of the pulmonary circulation before HF.
Key Words: Hypoplastic left heart syndrome Norwood procedure Haemodynamic status
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