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Eur J Cardiothorac Surg 2003;24:165-167
© 2003 Elsevier Science NL

Case report

Multidisciplinary management of giant malignant endo-thoracic nerve sheath tumor

Cardio-thoracic Surgery, Bristol Cardiothoracic Centre, Bristol Royal Infirmary, Marlborough Street, Bristol BS2 8HW, UK

Received 19 December 2002; received in revised form 10 March 2003; accepted 13 March 2003.

^* Corresponding author. Tel.: +44-117-928-3145; fax: +44-117-929-9737
e-mail: r.ascione{at}bristol.ac.uk

Malignant degeneration of neurogenic tumors has been reported to occur in 1–25% of patients with neurofibromatosis-I, and is the leading cause of cancer-related death in these patients. We report a case of multidisciplinary management of a giant malignant endothoracic nerve sheath tumor leading to histologically proven remission.

Key Words: Neurofibromatosis-I • Thoracic surgery • Multidisciplinary management