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Christian Hagl
Matthias Karck
Klaus Kallenbach
Rainer Leyh
Axel Haverich
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Eur J Cardiothorac Surg 2003;24:371-378
© 2003 Elsevier Science NL


Review

Hypothermic circulatory arrest during ascending and aortic arch surgery: the theoretical impact of different cerebral perfusion techniques and other methods of cerebral protection

Christian Hagla*, Nawid Khaladja, Matthias Karcka, Klaus Kallenbacha, Rainer Leyha, Michael Winterhalterb, Axel Havericha

a Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany
b Department of Anesthesiology, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany

Received 19 March 2003; received in revised form 3 May 2003; accepted 18 May 2003.

* Corresponding author. Tel.: +49-511-532-6581; fax: +49-511-532-5404
e-mail: hagl{at}thg.mh-hannover.de

Operations on the thoracic aorta using hypothermic circulatory arrest are still associated with significant morbidity and mortality due to neurological complications. During the last decades, different cerebral protection techniques have been introduced into clinical practice to reduce the incidence of such complications. Furthermore clinical as well as basic researches have been performed to improve the outcome after these operations. Currently different cerebral perfusion methods are in clinical use and the superiority of one or the other method is a matter of controversial discussion. This review has been undertaken to evaluate the theoretical impact of these different methods of cerebral protection. Based on the experience of the authors the pros and cons are discussed with clinical and experimental reports from the literature.




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