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Eur J Cardiothorac Surg 2003;24:614-619
© 2003 Elsevier Science NL
Department of Respiratory Medicine and Thoracic Surgery, Glenfield Hospital, Groby Road, Leicester LE3 9QP, UK
Received 24 October 2002; received in revised form 7 May 2003; accepted 24 June 2003.
* Corresponding author. Tel.: +44-116-256-3959; fax: +44-116-236-7768
e-mail: ingeroey{at}hotmail.com
Objectives: To correlate the long-term changes in respiratory physiology, body mass index (BMI) and health status after lung volume reduction surgery (LVRS). Patients/methods: From 1995 to 2002 77 patients; 48 male: 29 female, median age 59 (4172) years, have undergone LVRS (simultaneous bilateral in 27; staged bilateral in 3; unilateral in 47). FEV1, total lung capacity (TLC), residual volume (RV) and RV/TLC ratio were measured preoperatively and at 3 months, 6 months, 1 year, 2 years, 3 years and 4 years post surgery. At the same time interval health status was assessed by Euroquol and Short Form 36 (SF 36) questionnaires. Seventeen patients have died within 4 years of their operation (30 day mortality 5%). Results: The changes in FEV1 are only significantly improved for 1 year post LVRS, while the improvements in TLC and RV remain significant up to 3 years postoperatively. The improvements in BMI also persist for 3 years. The best scores in Euroquol and SF 36 are obtained 6 months after LVRS but are only significantly improved up to 1 year. Conclusion: The physiological effects of volume LVRS are lasting but initial improvements in health status decline more rapidly.
Key Words: Emphysema Lung volume reduction surgery Health status
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