HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Gernot Seebacher Wilfried Wisser Walter Klepetko Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Aigner, C. Articles by Klepetko, W. Search for Related Content PubMed PubMed Citation Articles by Aigner, C. Articles by Klepetko, W. Related Collections Lung - transplantation

Eur J Cardiothorac Surg 2004;25:179-183
© 2004 Elsevier Science NL

Lobar transplantation, split lung transplantation and peripheral segmental resection-reliable procedures for downsizing donor lungs

Department of Cardiothoracic Surgery, Vienna University, Waehringer Guertel 18-20, A-1090 Vienna, Austria

Received 3 September 2003; received in revised form 4 November 2003; accepted 10 November 2003.

^* Corresponding author. Tel.: +43-1-40-400-5644; fax: +43-1-40-400-5642
e-mail: walter.klepetko{at}akh-wien.ac.at

Objectives: The increasing scarcity of donor lungs, especially for small and pediatric recipients has stimulated the development of new operative techniques, which allow larger lungs to be downsized for use in smaller recipients. This approach has only recently gained widespread use—especially for highly urgent recipients—however, it is still not considered a standard procedure. Methods: This report reviews the Vienna University experience with cadaveric split lung transplantation, lobar transplantation and by means of peripheral resection size reduced lung transplantation within the years 2001–2002. Peri-operative complications and outcome of those patients were retrospectively analysed and compared to the patients undergoing standard single or double lung transplantation during the observation period. Results: During the observation period 98 primary lung transplantations were performed, of which 27 (27.6%) were size reduced transplantations. Size reduction was achieved by lobar transplantation (n=9), split lung transplantation (n=2) or peripheral segmental resection (n=16). There was no statistically significant difference between the size reduced and standard lung transplantation group with regard to the rate of bronchial healing problems (n=3/7; P=0.85) and the rate of post-operative bleeding (n=5/12; P=0.85). No other major thoracic surgical complications were observed. Three months survival rate was 85.2% in the size reduced group, compared to 92.9% in the standard group (P=0.13). Conclusions: Size reduced lung transplantation, including split lung transplantation, lobar transplantation and peripheral segmental resection, is a reliable procedure providing equal results compared to standard lung transplantation.

Key Words: Lung transplantation • Size reduced lung transplantation • Split lung • Lobar transplantation • Segmental resection

This article has been cited by other articles:

				C. Aigner, W. Wisser, S. Taghavi, G. Lang, P. Jaksch, D. Czyzewski, and W. Klepetko Institutional experience with extracorporeal membrane oxygenation in lung transplantation Eur. J. Cardiothorac. Surg., March 1, 2007; 31(3): 468 - 474. [Abstract] [Full Text] [PDF]

				G. M. Marta, C. Aigner, and W. Klepetko Split lung transplantation with intraoperative extracorporeal membrane oxygenation (ECMO) support MMCTS, August 9, 2005; 2005(0809): 984. [Abstract] [Full Text] [PDF]

				C. Aigner, G. Winkler, P. Jaksch, G. Seebacher, G. Lang, S. Taghavi, W. Wisser, and W. Klepetko Extended donor criteria for lung transplantation--a clinical reality Eur. J. Cardiothorac. Surg., May 1, 2005; 27(5): 757 - 761. [Abstract] [Full Text] [PDF]