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Eur J Cardiothorac Surg 2004;26:1047-1049
© 2004 Elsevier Science NL

Case report

A combined small cell carcinoma of the lung containing three components: small cell, spindle cell and squamous cell carcinoma

Second Department of Surgery, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kagawa 761-0793, Japan

Received 9 June 2004; received in revised form 1 August 2004; accepted 3 August 2004.

^* Corresponding author. Tel.: +81-87-891-2191; fax: +81-87-891-2192. (E-mail: mgotoh{at}kms.ac.jp).

A 61-year-old man was referred to our hospital because of rapid growth of a mass shadow revealed by chest radiography. The mass was diagnosed as pure small cell carcinoma by CT-guided needle biopsy, and the patient underwent chemotherapy. However, as the tumor showed no response, we considered the possibility of some other form of malignancy and performed surgery. Postoperatively, the mass was diagnosed as small cell carcinoma combined with small cell, spindle cell and squamous cell carcinoma. We report this case in view of the rarity of this combination of morphologic patterns in a primary bronchogenic carcinoma.

This article has been cited by other articles:

				M. F. Ismail, A. A. Mowafy, and S. I. Sameh A combined small cell carcinoma of the lung containing three components: small cell, spindle cell and squamous cell carcinoma, revisited Eur. J. Cardiothorac. Surg., April 1, 2005; 27(4): 734 - 734. [Full Text] [PDF]

				M. Gotoh, Y. Yamamoto, C.-L. Huang, and H. Yokomise Reply to Ismail Eur. J. Cardiothorac. Surg., April 1, 2005; 27(4): 735 - 735. [Full Text] [PDF]