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Eur J Cardiothorac Surg 2005;27:138-149
© 2005 Elsevier Science NL


Review

Heparin-induced thrombocytopenia in the cardiovascular patient: diagnostic and treatment guidelines

Ahmet Tayfun Gurbuz*, William G. Elliott, Ayhan A. Zia

Departments of Cardio-Thoracic Surgery and Cardiology, Tucson Medical Center, Tucson, AZ, USA

Received 6 July 2004; received in revised form 22 September 2004; accepted 24 September 2004.

* Corresponding author. Address: Southern Arizona Cardio-Thoracic Surgery, P.C., 4729 E. Sunrise Drive, Suite 153, Tucson, AZ 85718, USA. Tel.: +1 520 498 2355; fax: +1 520 498 2358. (E-mail: atgurbuz{at}yahoo.com).

Heparin-induced thrombocytopenia/thrombosis is an immunologic reaction to unfractionated heparin characterized by thrombocytopenia, platelet activation and thrombosis. A high index of suspicion is required for timely diagnosis and treatment. Treatment is complex and outcome maybe less then satisfactory.

Key Words: Heparin • Thrombocytopenia • Thrombosis




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T. Matsuo and K. Wanaka
Management of Uremic Patients With Heparin-Induced Thrombocytopenia Requiring Hemodialysis
Clinical and Applied Thrombosis/Hemostasis, October 1, 2008; 14(4): 459 - 464.
[Abstract] [PDF]




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