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Eur J Cardiothorac Surg 2005;27:191-201
© 2005 Elsevier Science NL
Invited paper |
a Denia, Alicante, Spain
b Clinic for Cardiac Surgery, Institute for Cardiovascular Diseases, UC Clinical Centre of Serbia, 8th Kosta Todorovic St., 11000 Belgrade, Serbia and Montenegro
c Alder Hey Royal Children Hospital, Liverpool, UK
d Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
e Department of Cardiology, Cardiac Imaging Unit, Hospital Sant Pau, Barcelona, Spain
f Department of Nuclear Medicine, Hospital Sant Pau, Barcelona, Spain
g Cardiocirculatory Unit, Investigation Centre, University Hospital La Fe, Valencia, Spain
h Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, NIH, Bethesda, MD, USA
Received 6 September 2004; received in revised form 25 November 2004; accepted 26 November 2004.
* Corresponding author. Tel.: +381 11 367 0609; fax: +381 11 361 0880. (E-mail: kocica{at}sezampro.yu). (URL: www.ctsnet.org/home/mkocica).
Structure and function in any organ are inseparable categories, both in health and disease. Whether we are ready to accept, or not, many questions in cardiovascular medicine are still pending, due to our insufficient insight in the basic science. Even so, any new concept encounters difficulties, mainly arising from our inert attitude, which may result either in unjustified acceptance or denial. The ventricular myocardial band concept, developed over the last 50 years, has revealed unavoidable coherence and mutual coupling of form and function in the ventricular myocardium. After more than five centuries long debate on macroscopic structure of the ventricular myocardium, this concept has provided a promising ground for its final understanding. Recent validations of the ventricular myocardial band, reviewed here, as well as future research directions that are pointed out, should initiate much wider scientific interest, which would, in turn, lead to reconciliation of some exceeded concepts about developmental, electrical, mechanical and energetical events in human heart. The benefit of this, of course, would be the most evident in the clinical arena.
Key Words: Ventricle • Anatomy • Myocardium • Physiology
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