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Eur J Cardiothorac Surg 2005;27:826-830
© 2005 Elsevier Science NL


Treatment of type B aortic dissection: endoluminal repair or conventional medical therapy?

Giovanni Dialetto*, Franco E. Covino, Giancarlo Scognamiglio, Sabrina Manduca, Alessandro Della Corte, Bruno Giannolo, Michelangelo Scardone, Maurizio Cotrufo

Department of Cardiothoracic and Respiratory Sciences, Division of Cardiovascular Surgery and Transplants, Second University of Naples, V Monaldi Hospital, 80131 Naples, Italy

Received 17 September 2004; received in revised form 24 January 2005; accepted 2 February 2005.

* Corresponding author. Address: Via Simone Martini, 76, Naples 80128, Italy. Tel.: +39 81 579 3001; fax: +39 81 546 4594. (E-mail: gdial{at}libero.it).

Objective: To evaluate the mid-term results of endovascular stent-grafting for type B aortic dissection, in comparison with those of standard medical therapy in uncomplicated cases. Methods: Between January 1999 and 2004, among 56 patients (mean age 59.5±11.5 years) with type B aortic dissection, hypotensive medical therapy was the only treatment in 28 uncomplicated cases, (group A), while stent-graft implantation was performed in 28 patients with uncontrolled hypertension, persistent pain or evidence of dissection progression or complication (group B). In 14 cases (50%) the procedure was performed in an acute setting. Stent-grafting procedures were monitored with intraoperative trans-esophageal echocardiography and cine-angiography. CT scan and trans-esophageal echocardiography were performed before hospital discharge, at 6 and 12 months and then yearly. Results: Follow-up (range 1–61 months, average 18.1±16.9 months) was 100% complete. In-hospital mortality was 10.7% (three patients, all belonging to Group B; P=0.24). No spinal cord injuries were observed. Early endoleak occurred in one patient (3.5%). Mid-term mortality was lower in Group B, although the difference was not significant (10.7 versus 14.3% in Group A, P=0.71). Follow-up CT scans evidenced complete thrombosis of the false lumen in 75% cases in Group B, 10.7% in Group A (P=0.0001), and an aneurismal dilatation of the descending aorta in 3.5% cases in Group B, 28.5% in Group A (P=0.02). Conclusions: Although with still considerable early mortality, endovascular stent-graft implantation is an effective option for the treatment of complicated type B aortic dissection. Endovascular treatment achieved a better mid-term fate of the descending thoracic aorta than medical therapy alone, even in patients with worse preoperative conditions.

Key Words: Descending aorta • Aortic dissection • Endovascular stent-graft • Hypotensive therapy




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