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Eur J Cardiothorac Surg 2005;27:882-886
© 2005 Elsevier Science NL
a 3rd Department of Cardiology, Silesian Centre for Heart Diseases, Medical University of Silesia, Szpitalna 2 Street, 41-800 Zabrze, Poland
b Department of Cardiac Surgery and Transplantation, Medical University of Silesia, Zabrze, Poland
Received 20 August 2004; received in revised form 27 December 2004; accepted 20 January 2005.
* Corresponding author. Tel.: +48 604 102 999/32 2732316; fax: +48 32 2732679. (E-mail: b.szygula{at}sccs.pl).
Objective: The efficacy of percutaneous and surgical revascularization in acute coronary syndromes without ST-segment elevation is similar. Therefore, other factors, like health-related quality of life, should play an important role in choosing the revascularization method. Methods: We compared 12-month health-related quality of life for high-risk patients with acute coronary syndromes without ST-segment elevation assigned to percutaneous coronary intervention (group A) versus coronary artery bypass graft surgery (group B). Patients had an episode of rest angina within 24h prior to admission and had to fulfil at least one of the criteria: (1) ST-segment depression (
0.05mV), (2) transient (<20min) ST-segment elevation or T-wave inversion (0.1mV), (3) positive serum cardiac markers. Four hundred and ninety-six (91.34%) of 543 patients alive 12-months after index hospitalization completed a Short Form-36 (SF-36) health status survey. Group A comprised 392 patients and group B comprised 104 patients. We compared mental component summary (MCS) and physical component summary (PCS) scores from the SF-36 survey between analyzed groups. Results: There were no significant differences in MCS scores (47.21±12.30 vs. 46.60±11.3 in group A and group B, respectively, NS). PCS scores were lower in group A (38.30±11.10 vs. 42.64±9.76; p=0.003). Patients of group A had a higher rate of unstable angina (22.45 vs. 5.77%, p=0.0002) and repeated revascularization (12.76 vs. 1.92%, p=0.001) at 1 year. Patients of group A also had higher systolic and diastolic blood pressure during follow-up (138.17±20.41 vs. 133.47±19.21, p=0.04 and 82.48±11.32 vs. 77.25±16.17, p=0.0003, respectively). Systolic blood pressure was inversely associated with PCS scores in group A (Spearman's R= –0.18 p=0.0007). Conclusions: This study has shown that there is a significant difference in health-related quality of life 12-months after percutaneous coronary intervention and coronary artery bypass graft surgery. This difference arises from better physical function (physical component summary) for coronary artery bypass graft surgery patients compared with percutaneous coronary intervention patients. Despite impairment of the physical health status (physical component summary), the mental health status (mental component summary) remained similar in both groups.
Key Words: Acute coronary syndromes without persistent ST segment elevation • Early invasive strategy • Coronary artery bypass grafting • Percutaneous coronary intervention • Health related quality of life • SF-36
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