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Eur J Cardiothorac Surg 2005;27:949-955
© 2005 Elsevier Science NL

Staged surgical repair of functional single ventricle in infants with unobstructed pulmonary blood flow

^a Section of Cardiothoracic Surgery, Indiana University School of Medicine, James W. Riley Hospital for Children, 545 Barnhill Dr., EH 215, Indianapolis, IN 46202-5123, USA
^b Section of Pediatric Cardiology, Indiana University School of Medicine, James W. Riley Hospital for Children, Indianapolis, IN, USA

Received 13 September 2004; received in revised form 12 January 2005; accepted 17 January 2005.

^* Corresponding author. Tel.: +1 317 274 7150; fax: +1 317 274 2940. (E-mail: jobrown{at}iupui.edu).

Objective: The infant with a functional single ventricle (SV) and unobstructed pulmonary blood flow (UPBF) requires early protection of the pulmonary vascular bed to ensure suitability for a subsequent Fontan procedure. Systemic obstruction by aortic arch obstruction, subaortic stenosis, or combination of both, has been widely recognized as an important risk factor for poor outcome in children with SV–UPBF who are palliated with pulmonary artery banding (PAB). We reviewed our experience with primary PAB in the subset of patients with SV–UPBF to identify risk factors for subsequent palliative procedures and Fontan completion. Methods: Between January 1990 and May 2004, 80 patients (median age, 14 days) with functional SV and UPBF underwent PAB as their primary palliative procedure. Thirty-five neonates had concomitant aortic coarctation or interrupted aortic arch repair (44%). A Damus–Kaye–Stansel procedure was subsequently performed in 19 patients, and subaortic resection or ventricular septal defect or bulboventricular foramen enlargement was performed in five. Results: There were 4 operative deaths, and 15 late deaths. The actuarial overall survival is 84% at 1 year, 76% at 5 and 15 years. Follow-up is complete in all but six children at a mean interval of 4.9±3.7 years (range, 2 months–15 years). Thirty-seven patients (49%; 37 of 76) have undergone the hemi-Fontan procedure (with three hospital deaths) and 40 patients (53%; 40 of 76; 12 children without previous hemi-Fontan) have undergone the completion Fontan procedure without mortality or Fontan takedown. Conclusion: In infants with single ventricle physiology with or without systemic outflow obstruction and unobstructed pulmonary blood flow, a strategy of pulmonary artery banding carries acceptable operative and mid-term mortality in a high-risk group of patients. Pulmonary artery banding does not compromise performance of subsequent Damus–Kaye–Stansel procedure or completion Fontan palliation.

Key Words: Pediatric • Congenital heart disease • Fontan • Univentricular heart

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