HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Pawelec-Wojtalik, M. Articles by Quereshi, S. A. Search for Related Content PubMed PubMed Citation Articles by Pawelec-Wojtalik, M. Articles by Quereshi, S. A. Related Collections Cardiac - other Congenital - acyanotic

Eur J Cardiothorac Surg 2006;29:89-92
© 2006 Elsevier Science NL

Comparison of cardiac function in children after surgical and Amplatzer occluder closure of secundum atrial septal defects

Magorztata Pawelec-Wojtalik ^a , Michal Wojtalik ^b , Wojciech Mrowczynski ^{b , _*} , Rafa Surmacz ^c , Shakeel Ahmed Quereshi ^d

^a Department of Paediatric Radiology, Pozna University of Medical Sciences, Poland
^b Department of Paediatric Cardiac Surgery, Pozna University of Medical Sciences, Poland
^c Department of Paediatric Cardiology and Nephrology, Pozna University of Medical Sciences, Poland
^d Department of Paediatric Cardiology, Guy's Hospital, London, UK

Received 19 May 2005; received in revised form 13 October 2005; accepted 17 October 2005.

^_* Corresponding author. Tel.: +48 61 8491 277; fax: +48 61 8669 130. (Email: wojciech.mrowczynski{at}amp.edu.pl).

Objective: The aim of the retrospective study was to examine the changes in the left and right ventricular size as well as the systolic and diastolic function of the left ventricle after surgical and transcatheter treatment of atrial septal defects with Amplatzer atrial septal defect occluder (ASDO). Methods: Two groups of patients were examined using transthoracic cross-sectional echocardiography before and after the treatment of atrial septal defect: Group A – Amplatzer ASD occluder – 38 children and Group S treated surgically – 20 children. The following parameters were assessed: left and right ventricular end-diastolic diameter indexes, ejection fraction, mitral E wave to A wave velocity ratio, deceleration time (DCT), isovolumetric relaxation time (IVRT) and heart rate. Results: There was a significant decrease in right ventricular and an increase in left ventricular size in both groups during the follow-up observation. The long-term ECHO examination revealed smaller right ventricle (RV) (Group A: RVEDI=1.00 ± 0.20 vs Group S RVEDI: 1.18 ± 0.20 (p = 0.001)) and bigger left ventricle (Group A: LVEDI = 1.04 ± 0.08 vs Group S: LVEDI = 0.99 ± 0.07 (p = 0.022)) in Group A in comparison to Group S. Children undergoing operation had significantly shorter IVRT (Group A: IVRT = 50.00 ± 9.65 vs Group S: IVRT = 42.5 ± 8.95 (p = 0.02)) than patients after ASDO device application. Conclusions: (1) During the follow-up period, the diastolic function of the left ventricle is better in children with device closure of ASD compared with those patients treated surgically. (2) Postoperative changes of the left and right ventricular size indexes are more favourable in patients after the device closure of ASD compared with children undergoing the surgical procedure.

Key Words: Atrial septal defect • Paediatric cardiac surgery • Amplatzer occluder • Systolic function • Diastolic function

This article has been cited by other articles:

				Y. Zhu, A. O. Gramolini, M. A. Walsh, Y.-Q. Zhou, C. Slorach, M. K. Friedberg, J. K. Takeuchi, H. Sun, R. M. Henkelman, P. H. Backx, et al. Tbx5-dependent pathway regulating diastolic function in congenital heart disease PNAS, April 8, 2008; 105(14): 5519 - 5524. [Abstract] [Full Text] [PDF]

				L. K. von Segesser Closure devices: the solution for repair of direct access apertures after valved stent implantation? Eur. J. Cardiothorac. Surg., July 1, 2006; 30(1): 2 - 3. [Full Text] [PDF]