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Eur J Cardiothorac Surg 2006;29:150-155
© 2006 Elsevier Science NL
Nanyang Technological University, 50 Nanyang Avenue, School of Mechanical and Aerospace Engineering, Division of Thermal and Fluids Engineering, Singapore 639798, Singapore
Received 17 October 2005; received in revised form 21 November 2005; accepted 2 December 2005.
* Corresponding author. Tel.: +65 90281501; fax: +65 90281501. (Email: wogoe{at}web.de).
Objective: New pericardial aortic bioprostheses (3F Therapeutics and temporarily stented autologous pericardial valve prosthesis) were developed recently. These valves are designed with commissures connected to the aortic wall at only three single points (single point attached commissures (SPAC)). The aim of this study was to investigate the forces acting on SPAC during varying pressure load. Methods: Aortic roots with diameters 19, 25, and 29 mm were made using silicone polymer. A bovine pericardial SPAC aortic valve prosthesis was constructed using a 3D-mold and was implanted in the silicone aortic root. The base of the valve was sutured onto the aortic annulus with 4-0 polypropylene running suture and each commissure was sutured to a miniaturized force transducer with only one 3-0 polypropylene U-stitch. Three silicon aortic roots of each size were pressurized up to 200 mmHg and forces on SPAC were measured. Results: All valves remained competent at a pressure of 200 mmHg. Recordings showed a linear correlation between applied pressure and forces measured at SPAC. At a pressure of 80 mmHg (equivalent to diastolic pressure), the forces were 0.44 ± 0.22 N, 1.15 ± 0.18 N, and 2.00 ± 0.35 N in annular diameters 19 mm, 25 mm, and 29 mm, respectively. It was observed, that the main forces were acting along the axial direction and not along the radial direction. Conclusions: Forces on "single point attached commissures" in pericardial aortic valves were measured. These forces were acting mainly in axial direction and not in radial direction. This knowledge is important for the implantation technique of SPAC pericardial aortic valves.
Key Words: Single point attached commissure SPAC Aortic valve prosthesis Commissure Force
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