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Eur J Cardiothorac Surg 2006;29:261-263
© 2006 Elsevier Science NL

Case report

Tracheal replacement with an aortic autograft

^a Thoracic and Vascular Unit, Avicenne Hospital, Bobigny, Paris XIII University, France
^b Thoracic and Cardio-Vascular Unit, CHU Limoges, France
^c Laboratoire d’Etude des Greffes et Prothèses Cardiaques, Hôpital Broussais, UPRES 264, Université Paris VI, France

Received 15 September 2005; received in revised form 17 November 2005; accepted 21 November 2005.

^_* Corresponding author. Tel.: +33 1 48955230/31; fax: +33 1 48955232. (Email: jacques.azorin{at}avc.aphp.fr).

Tracheal replacement after extensive resection remains a challenge for the thoracic surgeon. We propose an innovative solution: the use of an aortic autograft. After an experimental work on animals with aortic autografts and allografts [Martinod E, Seguin A, Pfeuty K, Fornes P, Kambouchner M, Azorin JF, Carpentier AF. Long-term evaluation of the replacement of the trachea with an autologous aortic graft. Ann Thorac Surg 2003;75(5):1572–8; Martinod E, Seguin A, Holder-Espinasse M, Kambouchner M, Duterque-Coquillaud M, Azorin JF, Carpentier AF. Tracheal regeneration following tracheal replacement with an allogenic aorta. Ann Thorac Surg 2005;79(3):942–8], we present the first human case of long tracheal replacement with an aortic autograft. In this case we replaced 7 cm of a tumoral trachea using an aortic infra-renal autograft supported by a silicone stent. The early postoperative course was uneventful. The stent was removed at three months. The patient died at six months from an acute pulmonary infection without any sign of anastomosis leakage or graft rupture. A new field of clinical study has to be investigated.

Key Words: Trachea • Tracheal replacement • Aortic autograft • Aortic allograft • Primary tracheal tumor

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