HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Venn, G. E. Articles by Goldstraw, P. Search for Related Content PubMed PubMed Citation Articles by Venn, G. E. Articles by Goldstraw, P.

European Journal of Cardio-Thoracic Surgery, Vol 3, 105-109, Copyright © 1989 by European Association for Cardio-thoracic Surgery

ARTICLES

Survival following pulmonary metastasectomy

GE Venn, S Sarin and P Goldstraw
Brompton, Middlesex and University College Hospitals, London, UK.

One hundred and fifty-six thoracic operations have been performed over an 8-year period, from 1980 to 1987, for 118 patients with pulmonary metastases. In 27 instances, the disease has been bilateral requiring a midline approach or sequential lateral thoracotomies. Resection was achieved by wedge excision in 74%, lobectomy in 16%, pneumonectomy in 4%, lobectomy plus wedge excision in 2%, bilobectomy in 1%, segmentectomy in 2% and segmentectomy plus wedge excision in 1%. The operative mortality for the group as a whole was 1.6% per patient (70% confidence limits CL. 0.6%-4.2%) and 1.2% per operation (70% CL. 0.5- 3.2%). Actuarial survival for the histological subgroups at 2 and 5 years were: carcinoma 50% (+/- 11% standard error) and 35% (+/- 12%), sarcoma 59% (+/- 10%) and 51% (+/- 12%), teratoma 89% (+/- 5%) and 84% (+/- 7%) respectively. No patient following resection for metastatic melanoma was alive at 2 years. The survival in the teratoma group was significantly higher than in the other groups (P less than 0.001 carcinoma; P less than 0.01 sarcoma; P less than 0.001 melanoma). Survival in all groups was significantly greater than for the melanoma group. Metastasectomy is well tolerated by the patient. Worthwhile longterm survival is obtained in those patients in whom the primary disease has been controlled and all secondary disease is encompassed by the proposed surgery.

This article has been cited by other articles:

				M. K. Gould, J. Fletcher, M. D. Iannettoni, W. R. Lynch, D. E. Midthun, D. P. Naidich, and D. E. Ost Evaluation of Patients With Pulmonary Nodules: When Is It Lung Cancer?: ACCP Evidence-Based Clinical Practice Guidelines (2nd Edition) Chest, September 1, 2007; 132(3_suppl): 108S - 130S. [Abstract] [Full Text] [PDF]

				O. Rena, E. Papalia, A. Oliaro, P. Filosso, E. Ruffini, G. Maggi, and C. Casadio Pulmonary metastases from epithelial tumours: late results of surgical treatment. Eur. J. Cardiothorac. Surg., August 1, 2006; 30(2): 217 - 222. [Abstract] [Full Text] [PDF]

				A. Rolle, A. Pereszlenyi, R. Koch, M. Richard, and B. Baier Is surgery for multiple lung metastases reasonable? A total of 328 consecutive patients with multiple-laser metastasectomies with a new 1318-nm Nd:YAG laser J. Thorac. Cardiovasc. Surg., June 1, 2006; 131(6): 1236 - 1242. [Abstract] [Full Text] [PDF]

				R. M. Suri, C. Deschamps, S. D. Cassivi, F. C. Nichols III, M. S. Allen, C. D. Schleck, and P. C. Pairolero Pulmonary Resection for Metastatic Malignant Fibrous Histiocytoma: An Analysis of Prognostic Factors Ann. Thorac. Surg., November 1, 2005; 80(5): 1847 - 1852. [Abstract] [Full Text] [PDF]

				A. Monteiro, N. Arce, J. Bernardo, L. Eugenio, and M. J. Antunes Surgical resection of lung metastases from epithelial tumors Ann. Thorac. Surg., February 1, 2004; 77(2): 431 - 437. [Abstract] [Full Text] [PDF]

				T. C. Mineo, V. Ambrogi, M. Paci, N. Iavicoli, E. Pompeo, and I. Nofroni Transxiphoid Bilateral Palpation in Video-Assisted Thoracoscopic Lung Metastasectomy Arch Surg, July 1, 2001; 136(7): 783 - 788. [Abstract] [Full Text] [PDF]

				V. Ambrogi, M. Paci, E. Pompeo, and T. C. Mineo Transxiphoid video-assisted pulmonary metastasectomy: relevance of helical computed tomography occult lesions Ann. Thorac. Surg., December 1, 2000; 70(6): 1847 - 1852. [Abstract] [Full Text] [PDF]

				J. H. Robert, V. Ambrogi, B. Mermillod, D. Dahabreh, and P. Goldstraw Factors Influencing Long-Term Survival After Lung Metastasectomy Ann. Thorac. Surg., March 1, 1997; 63(3): 777 - 784. [Abstract] [Full Text]

				The International Registry of Lung Metastases, Writing Committee:, U. Pastorino, M. Buyse, G. Friedel, R. J. Ginsberg, P. Girard, P. Goldstraw, M. Johnston, P. McCormack, et al. LONG-TERM RESULTS OF LUNG METASTASECTOMY: PROGNOSTIC ANALYSES BASED ON 5206 CASES J. Thorac. Cardiovasc. Surg., January 1, 1997; 113(1): 37 - 49. [Abstract] [Full Text]

				G. B. Ratto, S. Toma, D. Civalleri, G. C. Passerone, M. Esposito, D. Zaccheo, M. Canepa, P. Romano, R. Palumbo, F. De Cian, et al. ISOLATED LUNG PERFUSION WITH PLATINUM IN THE TREATMENT OF PULMONARY METASTASES FROM SOFT TISSUE SARCOMAS J. Thorac. Cardiovasc. Surg., September 1, 1996; 112(3): 614 - 622. [Abstract] [Full Text]

				K. Al-Kattan and P. Goldstraw COMPLETION PNEUMONECTOMY: INDICATIONS AND OUTCOME J. Thorac. Cardiovasc. Surg., October 1, 1995; 110(4): 1125 - 1129. [Abstract] [Full Text]

				L. Tafra, P. S. Dale, L. A. Wanek, K. P. Ramming, and D. L. Morton Resection and adjuvant immunotherapy for melanoma metastatic to the lung and thorax J. Thorac. Cardiovasc. Surg., July 1, 1995; 110(1): 119 - 129. [Abstract] [Full Text]