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European Journal of Cardio-Thoracic Surgery, Vol 3, 241-248, Copyright © 1989 by European Association for Cardio-thoracic Surgery
HK Dasmahapatra, RM Freedom, CA Moes, M Musewe, H Sherret, JG Coles, WG Williams and GA Trusler
During a 24-year period (1963-1987), 46 infants and children with complete
transposition of the great arteries (CTGA) and an essentially intact
ventricular septum (IVS) have undergone surgical relief of left ventricular
outflow tract obstruction (LVOTO) concurrently with the Mustard operation
(MO). The obstruction was valvar in 2 patients, subvalvar in 43 and
combined valvar and subvalvar in 1; the ventricular septum was intact in
42, and 4 patients had a small VSD at the time of repair. Neonatal and
pre-Mustard cardiac catheterization (CC) data were analyzed to obtain LV to
right ventricular peak systolic pressure ratio (LV/RVPSP) and LVOT peak
systolic gradient (PSG). The mean neonatal LV/RVPSP (n = 31) was 0.79 +/-
0.04; pre-Mustard LV/RVPSP (n = 44) was 0.75 +/- 0.05; pre-Mustard LVOT PSG
(n = 34) was 46.5 +/- 3.5 mmHg. Neonatal (n = 29) and pre-Mustard (n = 30)
cardiac angiograms were retrospectively reviewed to analyse morphologic
substrates of LVOTO. In the neonatal period, LVOTO was present in 7
patients (anatomic, n = 4; dynamic, n = 2; combined, n = 1). Immediately
prior to the MO, LVOTO was present in 29 (anatomic, n = 20; dynamic n = 2;
combined, n = 7). Techniques to correct LVOTO at the initial MO included
pulmonary valvotomy (n = 3), ventriculomyectomy (n = 41), resection of an
windsock aneurysm (n = 1), LV to pulmonary artery valved conduit (VC) (n =
1). Two patients underwent VC early postoperatively (PO) for severe
residual LVOTO (both died).(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Surgical experience with left ventricular outflow tract obstruction in patients with complete transposition of the great arteries and essentially intact ventricular septum undergoing the Mustard operation
Division of Cardiovascular Surgery, Hospital for Sick Children, Toronto, Canada.
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