HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hutter, J. A. Articles by Wallwork, J. Search for Related Content PubMed PubMed Citation Articles by Hutter, J. A. Articles by Wallwork, J.

European Journal of Cardio-Thoracic Surgery, Vol 3, 300-303, Copyright © 1989 by European Association for Cardio-thoracic Surgery

ARTICLES

Heart-lung transplantation at Papworth Hospital

JA Hutter, JP Scott, P Deespins, S Stewart, T Higenbottam and J Wallwork
Department of Surgery, Papworth Hospital, Papworth Everard, Cambridgeshire, UK.

Combined heart-lung transplantation has been performed in 51 patients since 1984. A pulmonary preservation fluid preceded by prostacyclin infusion has allowed distant procurement. Early organ function has been good in all cases. Maintenance immunosuppression is cyclosporine and azathioprine. Steroids are given to treat rejection episodes. Transbronchial biopsy has allowed the accurate, early and safe diagnosis of rejection. Acute cardiac rejection has not occurred in these patients. Thirty-seven patients are alive between 1 and 54 months following transplantation. The actuarial survival at 1 year is 76% and 68% at 2 years. Four patients died in the early postoperative period as a result of primary Cytomegalovirus (CMV). Other causes of early death were bacterial infection (4), cerebrovascular event (1), tracheal dehiscence (1) and small bowel infarction following retransplantation for obliterative bronchiolitis. Three other patients have died as a result of obliterative bronchiolitis. Patients and donors have been carefully selected to ensure that this scarce resource is utilised most effectively.

This article has been cited by other articles:

				G. HANANIA Management of anticoagulants during pregnancy Heart, August 1, 2001; 86(2): 125 - 126. [Full Text] [PDF]

				M. K. Pasque, E. P. Trulock, J. D. Cooper, A. N. Triantafillou, C. B. Huddleston, M. Rosenbloom, S. Sundaresan, J. L. Cox, and G. A. Patterson Single Lung Transplantation for Pulmonary Hypertension : Single Institution Experience in 34 Patients Circulation, October 15, 1995; 92(8): 2252 - 2258. [Abstract] [Full Text]