HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Milano, A. Articles by Gallucci, V. Search for Related Content PubMed PubMed Citation Articles by Milano, A. Articles by Gallucci, V.

European Journal of Cardio-Thoracic Surgery, Vol 3, 312-319, Copyright © 1989 by European Association for Cardio-thoracic Surgery

ARTICLES

Mitral valve replacement with the Hancock, Bjork-Shiley and Lillehei- Kaster prostheses. A comparison based on a 15-year follow-up

A Milano, U Bortolotti, A Mazzucco, F Guerra, A Magni, G Stellin and V Gallucci
Department of Cardiovascular Surgery, University of Padova Medical School, Italy.

The performance of the standard Hancock porcine bioprosthesis (HPB), the Bjork-Shiley spherical disc prosthesis (BSP) and the Lillehei- Kaster tilting disc prosthesis (LKP) was compared over a 15-year follow- up in patients who underwent isolated mitral valve replacement (502 HPB, 183 LKP and 119 BSP). The cumulative duration of follow-up is 3,488 patient-years (mean, 8.0 +/- 3.7 years) for patients with a HPB, 1,302 patient-years (mean, 8.4 +/- 4.9 years) for patients with a LKP and 718 patient-years (mean, 7.1 +/- 5.6 years) for those with a BSP. At 15 years a significant difference was found among the 3 groups in freedom from (1) anticoagulant-related haemorrhages, between HPB (83% +/- 7%) and BSP (65% +/- 8%) recipients (P less than 0.05); (2) prosthetic dysfunction, BSP (96% +/- 3%) and LKP (83% +/- 6%) versus HPB (42% +/- 5%) recipients (P less than 0.001); (3) overall reoperations, BSP (94% +/- 3%) and LKP (89% +/- 3%) versus HPB (40% +/- 5%) recipients (P less than 0.001) and (4) prosthetic failure, BSP (88% +/- 4%) and LKP (71% +/- 6%) versus HPB (38% +/- 5%) recipients (P less than 0.001). No difference was found in actuarial survival, freedom from thromboembolic episodes, treatment failure and overall prosthesis- related complications. Our results confirm that the long-term performance of the HPB in the mitral position is adversely affected by the high incidence of tissue degeneration while haemorrhagic complications may limit the advantage of the longer durability of mechanical prostheses.(ABSTRACT TRUNCATED AT 250 WORDS)

This article has been cited by other articles:

				A. Mazzucco, P. Morea, A. Milano, and U. Bortolotti Concentric wear of the Delrin disc of a Bjork-Shiley prosthesis: An uncommon cause of prosthetic incompetence J. Thorac. Cardiovasc. Surg., January 1, 1994; 107(1): 318 - 319. [Full Text]