HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Masahiro Ueno Ryuzo Sakata Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Matsumoto, K. Articles by Sakata, R. Search for Related Content PubMed PubMed Citation Articles by Matsumoto, K. Articles by Sakata, R. Related Collections Coronary disease

Eur J Cardiothorac Surg 2006;30:592-596
© 2006 Elsevier Science NL

Effects of ultrasonic skeletonization on internal thoracic and gastroepiploic arteries for coronary artery bypass grafting

^a Second Department of Surgery, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan
^b Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan

Received 24 February 2006; received in revised form 14 July 2006; accepted 24 July 2006.

^_* Corresponding author. Tel.: +81 99 275 5368; fax: +81 99 265 8177. (Email: kazuhisa{at}m3.kufm.kagoshima-u.ac.jp).

Objective: There are few data available on the effect of ultrasonic skeletonization with the harmonic scalpel on internal thoracic artery (ITA) and gastroepiploic artery (GEA) vessel function. Methods: Rings of segments of the skeletonized ITA, pedicled ITA, skeletonized GEA, and pedicled GEA were studied. Arterial segments were treated with high KCl and norepinephrine (NE) to obtain smooth muscle contractions. Endothelium-dependent and independent vasorelaxant potencies in 10^–6 mol/l NE-pre-constricted arteries were assessed by acetylcholine (ACh), and isosorbide dinitrate (ISDN) and diltiazem, respectively. Results: There were no differences in contractile potencies induced by high KCl and NE between the rings cut from skeletonized and pedicled grafts. The rings from skeletonized and pedicled vessels also showed equal sensitivity to ISDN and diltiazem. However, the rings from pedicled grafts showed greater relaxation responses to ACh than rings from skeletonized grafts. Conclusion: Ultrasonic complete skeletonization with the harmonic scalpel may retain smooth muscle function of skeletonized grafts, whereas endothelial function of ultrasonic skeletonized grafts may be significantly compromised.

Key Words: Ultrasonic scalpel • Skeletonization • Vascular function • Internal thoracic artery • Gastroepiploic artery

This article has been cited by other articles:

				J. Shi, T. Iesaki, N. Kubota, K. Sumiyoshi, K. Kajimoto, K. Kikuchi, H. Daida, and A. Amano Skeletonization with an ultrasonic scalpel is as safe as a non-skeletonized dissection in preserving the endothelial function of the human gastroepiploic artery Interactive CardioVascular and Thoracic Surgery, February 1, 2009; 8(2): 216 - 220. [Abstract] [Full Text] [PDF]

				P. Laje and M. Martinez-Ferro Thoracoscopic double aortic arch division with Harmonic scalpel: A case report J. Thorac. Cardiovasc. Surg., March 1, 2007; 133(3): 819 - 820. [Full Text] [PDF]