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Eur J Cardiothorac Surg 2007;31:242-248. doi:10.1016/j.ejcts.2006.10.035
Copyright © 2007, European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved

One-stage total repair of aortic arch anomaly using regional perfusion

Hong-Gook Limb, Woong-Han Kima,*, Woo-Sung Janga, Cheong Lima, Jae Gun Kwaka, Cheul Leeb, Seong Wook Hwangb, Chang-Ha Leeb

a Department of Thoracic and Cardiovascular Surgery, Clinical Research Institute, Seoul National University Children's Hospital, College of Medicine, Seoul National University, Seoul, Republic of Korea
b Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute, Bucheon, Republic of Korea

Received 2 September 2006; received in revised form 18 October 2006; accepted 23 October 2006.

* Corresponding author. Address: Department of Thoracic & Cardiovascular Surgery, Seoul National University, College of Medicine, Seoul National University Children's Hospital, 28 Yongon-Dong, Jongno-Gu, Seoul 110-744, Republic of Korea. Tel.: +82 2 2072 3637; fax: +82 2 3672 3637. (Email: woonghan{at}snu.ac.kr).

Objective: Primary repair of aortic arch obstructions and associated cardiac anomalies is a surgical challenge in neonates and infants. Deep hypothermic circulatory arrest prolongs myocardial ischemia and might induce cerebral and myocardial dysfunction. Methods: From March 2000 to December 2005, 69 neonates or infants with aortic arch anomaly underwent one-stage biventricular repair with continuous cerebral perfusion in the presence of a nonworking beating heart using the dual perfusion technique on the innominate artery and aortic root. Preoperative diagnoses of arch anomaly comprised aortic coarctation (n = 54) or an interrupted aortic arch (n = 15). Combined anomalies were ventricular septal defect (n = 52), anomalous origin of the right pulmonary artery from ascending aorta (n = 3), hypoplastic left heart syndrome (n = 2), truncus arteriosus (n = 2), atrioventricular septal defect (n = 2), double outlet right ventricle (n = 1), total anomalous pulmonary venous return (n = 1), partial anomalous pulmonary venous return (n = 1), and aortic stenosis (n = 1). Results: The mean regional perfusion time was 27.8 ± 9.8 min. There was no operative mortality. Postoperative low cardiac output was present in four patients (5.8%). A neurologic complication was noted in one patient (1.5%) who developed transient chorea, but recovered completely. During 32.8 ± 17.5 months of follow-up, one late death (1.5%) occurred. There was neither reoperation associated with arch anomaly nor recoarctation except in one patient. One patient developed left main bronchial compression necessitating aortopexy. Conclusions: One-stage total arch repair using our regional perfusion technique is an excellent method that may minimize neurologic and myocardial complications without mortality. Our surgical strategy for arch anomaly has a low rate of residual and recurrent coarctation when performed in neonates and infants.

Key Words: CHD, great vessel anomalies • Aortic arch • Coarctation • CPB, circulatory arrest • Neurocognitive deficits




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J. G. Kwak, W.-H. Kim, A. Y. Oh, T. G. Yoon, H.-S. Kim, J. H. Chae, and S. Y. Park
Is unilateral brain regional perfusion neurologically safe during congenital aortic arch surgery?
Eur. J. Cardiothorac. Surg., November 1, 2007; 32(5): 751 - 755.
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Copyright © 2007 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.