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Eur J Cardiothorac Surg 2007;31:955-957. doi:10.1016/j.ejcts.2007.01.039
Copyright © 2007, European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved

Case reports

The evolution of a pleural nodule into a giant fibrous tumor associated with hypoglycemic coma

Antonio D’Andrilli*, Claudio Andreetti, Mohsen Ibrahim, Erino A. Rendina

Department of Thoracic Surgery, University of Rome "La Sapienza", "Sant’Andrea" Hospital, Rome, Italy

Received 7 November 2006; received in revised form 12 January 2007; accepted 23 January 2007.

* Corresponding author. Address: Division of Thoracic Surgery, Sant’Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy. Tel.: +39 0633775633; fax: +39 0633775003. (Email: adandrilli{at}hotmail.com).

We hereby present the exceptional case of hypoglycemic coma associated with a giant benign localized fibrous tumor of the pleura (LFTP). A 79-year-old woman was found to have a small peripheral nodular lesion in the right hemithorax 7 years ago. A fine needle aspiration biopsy provided a diagnosis of LFTP, but the patient refused surgery. Six years later hypoglycemic coma and respiratory insufficiency appeared in association with a giant mass completely filling the right chest and shifting the mediastinum contralaterally. The tumor was completely resected, and complete relief of the hypoglycemic and respiratory symptoms was achieved. The patient is in good metabolic and respiratory conditions and disease-free 14 months after the operation.

Key Words: Localized fibrous tumor of the pleura • Pleural neoplasm • Hypoglycemia






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Copyright © 2007 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.