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Eur J Cardiothorac Surg 2008;33:315-316. doi:10.1016/j.ejcts.2007.10.022
Copyright © 2008, European Association for Cardio-thoracic Surgery. Published by Elsevier. All rights reserved.

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Hideaki Mori
Hiroshi Date
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Right arrow Lung - cancer


Case report

Induction chemoradiotherapy prior to surgery for non-small cell lung cancer invading the left atrium

Shinichi Toyookaa,*, Hideaki Moria, Katsuyuki Kiurab, Hiroshi Datea

a Department of Cancer and Thoracic Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Okayama 700-8558, Japan
b Department of Hematology, Oncology and Respiratory Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Okayama 700-8558, Japan

Received 23 August 2007; received in revised form 9 October 2007; accepted 29 October 2007.

* Corresponding author. Tel.: +81 86 235 7265; fax: +81 86 235 7269. (Email: toyooka{at}md.okayama-u.ac.jp).

We present a case of a 58-year-old man with diagnosis of lung adenocarcinoma invading the left atrium. He was treated with induction chemoradiotherapy for T4N1M0 disease, showing objective response. Then, a left upper lobectomy with a partial resection of the left atrium was performed without cardiopulmonary bypass. No residual tumor cells existed in the resected specimens, showing pathological complete response. Our case suggests that induction chemoradiotherapy prior to surgery can be an appropriate strategy among carefully selected patients with non-small cell lung cancer invading the left atrium.

Key Words: Lung cancer • Neoadjuvant therapy • Left atrium • Cardiopulmonary bypass







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Copyright © 2008 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.