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Long-term results of redo gastro-esophageal reflux disease surgery

University of the Mediterranean, Faculty of Medicine, Department of Thoracic surgery and Diseases of the Oesophagus, Sainte Marguerite University Hospital, Marseille, France

Received 12 June 2007; received in revised form 6 January 2008; accepted 15 January 2008.

^_* Corresponding author. Address: Department of Thoracic surgery, Sainte Marguerite University Hospital – CHU Sud, 270 Boulevard Ste Marguerite, 13274 Marseille Cedex 9, France. (Email: pathomas{at}ap-hm.fr).

Objective: To review the long-term results of redo gastro-esophageal reflux disease (GERD) surgery with special emphasis on residual acid-suppressing medications, pH monitoring results, and quality of life. Methods: Retrospective analysis of 52 patients (24 males) who underwent redo GERD surgery between 1986 and 2006 through a transthoracic (n = 14), or a transabdominal (n = 38) approach. Indications were recurrent GERD in 41 patients, and complication of the initial surgery in 11. Quality of life was evaluated by telephone enquiry using a validated French questionnaire (reflux quality score, RQS). Results: Postoperative complications occurred in 18 patients (35%), resulting in one death (2%). Reoperation was required in seven patients. At 1 year, 26 patients (51%) had 24 h pH monitoring, among whom 2 (8%) were proved to have recurrence of GERD. RQS values were calculated in 38 patients with a mean follow-up of 113 months. Fifty percent of this subgroup had a RQS value beyond 26/32, indicating an excellent quality of life. Among these 38 patients, 20 (53%) had acid-suppressing medications whatever their RQS values. Patients who underwent transthoracic GERD surgery had the highest RQS values (p = 0.02), a lower rate of complications (p = 0.06) and a lower rate of reoperation (p = 0.04). Conclusion: Our experience confirms that selection of candidates for redo GERD surgery is a challenging issue. A transthoracic approach seems to produce better results and lower rates of complications.

Abbreviations: GERD = gastro-esophageal reflux disease • RQS = reflux quality score

Key Words: Gastro-esophageal reflux disease • Redo surgery • Transthoracic approach • Long-term follow-up • Quality of life