EJCTS Click here to go to Edwards website
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Eur J Cardiothorac Surg 2008;33:1144-1145. doi:10.1016/j.ejcts.2008.03.018
Copyright © 2008, European Association for Cardio-thoracic Surgery. Published by Elsevier. All rights reserved.
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Reyes, G.
Right arrow Articles by Duarte, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Reyes, G.
Right arrow Articles by Duarte, J.
Related Collections
Right arrow Cardiac - pharmacology
Right arrow Cardiac - other
Right arrow Great vessels

Case reports

Management of massive pulmonary embolism using recombinant activated Factor VII

Guillermo Reyesa,*, Nieves Carrascob, Teresa Muñozb, Juan Duartea

a Department of Cardiovascular Surgery, Hospital Universitario La Princesa, c/Diego de León 62, 28006, Madrid, Spain
b Department of Intensive Care Unit, Hospital Universitario La Princesa, c/Diego de León 62, 28006, Madrid, Spain

Received 25 December 2007; received in revised form 23 February 2008; accepted 4 March 2008.

* Corresponding author. Address: Avda. de Cantabria 19 4°4, 28042 Madrid, Spain. Tel.: +34 91 5202268; fax: +34 91 5202286. (Email: guillermo_reyes_copa{at}yahoo.es).

Massive pulmonary embolism with concomitant intracranial haemorrhage is a condition associated with high mortality. Emergency embolectomy is indicated in those cases in which medical treatment is not possible. The case of a 65-year-old woman with massive pulmonary embolism after cranial trauma with intracranial haemorrhage and two cardiac arrests prior to surgery is described. The patient suffered a right ventricular failure requiring 6 h of extracorporeal circulation. After surgery a bleeding disorder happened despite conventional treatment. The patient was transferred to the ICU with packing. Despite the recent thrombotic event recombinant activated Factor VII (70 µg/kg) was used and the bleeding controlled. No other complications occurred and she was discharged 1 month later. As far as we know this is the first time that recombinant activated Factor VII has been used after a massive pulmonary embolism.

Key Words: Pulmonary embolism • Recombinant activated Factor VII • Bleeding






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2008 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.