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Eur J Cardiothorac Surg 2008;34:313-317. doi:10.1016/j.ejcts.2008.04.004
Copyright © 2008, European Association for Cardio-thoracic Surgery. Published by Elsevier. All rights reserved.
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Right arrow Congenital - acyanotic
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Right arrow Transplantation - heart

Reviews

Heart transplantation after congenital heart surgery: improving results and future goals

Jacob Simmonds, Michael Burch, Helen Dawkins, Victor Tsang*

Great Ormond Street Hospital for Children, London, UK

Received 4 December 2007; received in revised form 31 March 2008; accepted 2 April 2008.

* Corresponding author. Address: Department of Cardiothoracic Surgery, Great Ormond Street Hospital for Children, London WC1N 3JH, UK. Tel.: +44 207 405 9200; fax: +44 207 813 8440. (Email: tsangv{at}gosh.nhs.uk).

With growing numbers of children with complex congenital heart disease surviving initial surgical procedures, more patients are presenting in later childhood or early adulthood in cardiac failure. This presents an obvious increased burden on transplant centres, and a further strain on a limited donor pool. Historically, results for heart transplant following congenital heart disease (CHD) have been worse than those following cardiomyopathy. With increased surgical experience and intensive care expertise, the gap between the two aetiologies in our practice is decreasing. This article reviews the current protocols for transplantation in this setting, presenting a large single-centre experience over 20 years, and speculates on possible future advancements in this very challenging field.

Key Words: Congenital heart disease • Heart transplantation • Paediatrics






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Copyright © 2008 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.