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Department of Surgery, Semmelweis University, Budapest, Üll
i u. 78. 1082, Hungary
Received 19 December 2007; received in revised form 20 May 2008; accepted 11 June 2008.
* Corresponding author. Tel.: +36 1 313 5216; fax: +36 1 314 3431. (Email: balazsdr{at}gmail.com).
Objective: Esophagorespiratory fistulas developing from malignant tumors have serious complications by maintaining continuous airway contamination. The objective was to reveal the incidence, causes and characteristics of fistula formation and to examine the possibilities and efficiency of the treatment. Methods: In a single-center study between 1984 and 2004, the data of 2113 patients with tumorous esophageal stenosis were analyzed. Esophagorespiratory fistulas were detected in 264 cases (12.5%). Successful esophageal intubation, stent correction or replacement was performed in 188 cases, while there was one lethal complication. Twenty-seven patients had an intervention for nutritional support: 25 gastrostomies, 1 jejunostomy and 1 percutaneous endoscopic gastrostomy. Results: The mean survival period of all patients was 2.8 months; patients with implanted endoprosthesis 3.4 months; with nutritional support 1.1 months and with only supportive therapy 1.3 months, respectively. The differences between the endoprosthesis implanted group and the other two groups were significant (p < 0.001). Conclusions: By sealing the fistula, a successful endoscopic esophageal intubation ends the severe respiratory contamination and the inability to swallow, improving the quality of life and survival period. After the procedure, it is the malignant tumor and not the fistula that determines the future of the patient.
Key Words: Esophageal cancer Esophagorespiratory fistula Endoprosthesis Esophageal stents
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