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Review

Management strategies for interrupted aortic arch with associated anomalies

Department of Cardiac Surgery, Guys and St Thomas Hospital, NHS Trust, London, UK

Received 9 October 2008; received in revised form 26 December 2008; accepted 30 December 2008.

^_* Corresponding author. Address: 15 Grindley Hill Court, Hilton Road Stoke on Trent, ST4 6TA Staffordshire, UK. Tel.: +44 116 2563059; fax: +44 116 2502684. (Email: mishrapk_25{at}yahoo.com).

Interrupted aortic arch (IAA) is characterised by a lack of luminal continuity between the ascending and descending thoracic aorta. It represents a critical ductus dependent congenital heart disease, which without surgery is associated with high mortality in the neonatal period. Management remains challenging, although in recent years overall mortality appears to be improving. Long-term morbidity and need for repeated interventions are areas of concern. It is difficult to make generalised recommendations based on this literature review as complex associated anomalies often require individualised management strategy.

Key Words: Congenital heart disease • Aorta • Interrupted aortic arch • Associated anomalies