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Review

Current treatment paradigms of superior sulcus tumours

Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria

Received 28 November 2008; received in revised form 23 March 2009; accepted 14 April 2009.

^_* Corresponding author. Address: Waehringer Guertel 18-20, 1090 Vienna, Austria. Tel.: +43 1 40400 5644; fax: +43 1 40400 5642. (Email: walter.klepetko{at}meduniwien.ac.at).

Pancoast or superior pulmonary sulcus tumours are a rare subset of non-small-cell lung carcinomas (NSCLCs) which occur with an incidence of less than 5% of all lung cancers. Today, induction chemoradiation followed by surgical resection has become the established standard treatment approach for patients with sulcus superior tumours in the absence of other contraindications. This review focusses on the historical change of the treatment strategy, the evolution of surgical and multimodality management of this disease and the most recent published clinical outcome data of patients suffering from superior pulmonary sulcus carcinoma.

Key Words: Pancoast tumour • Sulcus superior tumour • Induction therapy • Radiotherapy • Surgery