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European Journal of Cardio-Thoracic Surgery, Vol 4, 653-657, Copyright © 1990 by European Association for Cardio-thoracic Surgery
C Jie, AM Wever, HA Huysmans, HC Franken, J Wever-Hess and J Hermans
All evaluable patients (n = 920) with primary non-small-cell lung cancer
(NSCLC) who were presented for surgery in our hospital between 1969 and
1985 were reviewed as to histological findings, postoperative stage, age
group and surgical procedure. Time trend analyses showed a significant
increase over time in the proportion of adenocarcinomas (p = 0.025) and in
the proportion of the elderly (greater than or equal to 70 years; p =
0.014). The 5-year survival rates by year of operation showed no
improvement at all over time; on the contrary they showed a decline, which
however only reached significance for patients who underwent pneumonectomy
(p = 0.034). It is noted that the overall survival curves up to 5 years
showed no significant differences between patients with adenocarcinoma and
patients with squamous cell carcinoma, or between patients aged 70 years or
more and patients aged 60-69 years. Despite expanded preoperative
diagnostic techniques and developments in surgical treatment, no
improvement in the survival after surgery for NSCLC over the period
1969-1985 could be established.
ARTICLES
Time trends and survival in patients presented for surgery with non- small-cell lung cancer 1969-1985
Department of Pulmonology, University Hospital, Leiden, The Netherlands.
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