HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Fradet, G. Articles by Wallwork, J. Search for Related Content PubMed PubMed Citation Articles by Fradet, G. Articles by Wallwork, J.

European Journal of Cardio-Thoracic Surgery, Vol 4, 136-140, Copyright © 1990 by European Association for Cardio-thoracic Surgery

ARTICLES

Cystic fibrosis: a new challenge for cardiothoracic surgery

G Fradet, RL Smyth, JP Scott, E Solis, L Sharples, TW Higenbottam and J Wallwork
Department of Transplantation Surgery, Papworth Hospital, Cambridgeshire, UK.

Cystic fibrosis (CF) is the most common fatal inherited disease in caucasian populations. Between 80-120 CF patients die each year in England and Wales, the majority from pulmonary disease. Since October 1985, 17 patients with CF have undergone heart-lung transplantation (HLT) at our institution. Only 3 early deaths have occurred in the first 2 postoperative months. Another patient died 9 months after transplantation. Thirteen patients are now alive 1-46 months (mean 14 month) post transplantation. Actuarial survival at 6 months is 80% for CF patients compared to 73% for non-CF patients. Both groups of patients have similar profiles of rejection and infection. In the Caucasian population, CF patients form the largest potential recipient group for HLT and our experience suggests that those CF patients who undergo HLT have a favourable outcome.