| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
European Journal of Cardio-Thoracic Surgery, Vol 8, 194-198, Copyright © 1994 by European Association for Cardio-thoracic Surgery
AD Cochrane, M Siddins, FL Rosenfeldt, R Salamonsen, L McConaghy, S Marasco and BB Davis
Despite the widespread use of amiodarone in non-surgical patients, its role
in the management of supraventricular tachyarrhythmias after cardiac
surgery is not clear. We set out to compare the relative efficacy of
amiodarone and digoxin in the management of atrial fibrillation and flutter
in the early postoperative period. This prospective randomised trial
comprised 30 patients, previously in sinus rhythm, who developed sustained
atrial fibrillation or flutter following myocardial revascularisation,
valve surgery or combined procedures. Amiodarone was administered as an
intravenous loading dose followed by a continuous infusion. Digoxin was
given as an intravenous loading dose followed by oral maintenance therapy.
Electrocardiographic and haemodynamic monitoring was continued for 24 h
after the commencement of treatment. There was a marked reduction in heart
rate in both groups, mainly in the first 6 h, from 146 to 89 beats per
minute in the amiodarone group and from 144 to 95 in the digoxin group. At
the end of the 24 h, one of the 15 patients in the amiodarone group and 3
of the 15 patients in the digoxin group remained in atrial fibrillation. No
patient in either group developed adverse reactions. We conclude that
intravenous amiodarone therapy is safe and at least as effective as digoxin
in the initial management of arrhythmias after cardiac surgery.
ARTICLES
A comparison of amiodarone and digoxin for treatment of supraventricular arrhythmias after cardiac surgery
C.J.O.B. Cardiac Surgery Unit, Alfred Hospital, Prahran, Victoria, Australia.
This article has been cited by other articles:
|
|
 |
|
  M. A. Albert, N. Halevy, and E. M. Antman Preoperative Evaluation for Cardiac Surgery Card. Surg. Adult, January 1, 2008; 3(2008): 261 - 280. [Full Text]
|
|
|
|
 |
|
 J. Dunning, T. Treasure, M. Versteegh, S. A.M. Nashef, and on behalf of the EACTS Audit and Guidelines Commit Guidelines on the prevention and management of de novo atrial fibrillation after cardiac and thoracic surgery Eur. J. Cardiothorac. Surg., December 1, 2006; 30(6): 852 - 872. [Full Text] [PDF]
|
|
|
|
 |
|
 E. A. Martinez, E. B. Bass, and P. Zimetbaum Pharmacologic Control of Rhythm: American College of Chest Physicians Guidelines for the Prevention and Management of Postoperative Atrial Fibrillation After Cardiac Surgery Chest, August 1, 2005; 128(2_suppl): 48S - 55S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. A. Martinez, A. E. Epstein, and E. B. Bass Pharmacologic Control of Ventricular Rate: American College of Chest Physicians Guidelines for the Prevention and Management of Postoperative Atrial Fibrillation After Cardiac Surgery Chest, August 1, 2005; 128(2_suppl): 56S - 60S. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Dunning, N. Khasati, and B. Prendergast What is the optimal medical treatment for stable cardiac surgical patients who go into atrial fibrillation after their operation? Interactive CardioVascular and Thoracic Surgery, March 1, 2004; 3(1): 46 - 51. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. M. Letelier, K. Udol, J. Ena, B. Weaver, and G. H. Guyatt Effectiveness of Amiodarone for Conversion of Atrial Fibrillation to Sinus Rhythm: A Meta-analysis Arch Intern Med, April 14, 2003; 163(7): 777 - 785. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Albert and E. M. Antman Preoperative Evaluation for Cardiac Surgery Card. Surg. Adult, January 1, 2003; 2(2003): 235 - 248. [Full Text]
|
|
|
|
 |
|
 G Nichol, F McAlister, B Pham, A Laupacis, B Shea, M Green, A Tang, and G Wells Meta-analysis of randomised controlled trials of the effectiveness of antiarrhythmic agents at promoting sinus rhythm in patients with atrial fibrillation Heart, June 1, 2002; 87(6): 535 - 543. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. H. Maisel, J. D. Rawn, and W. G. Stevenson Atrial Fibrillation after Cardiac Surgery Ann Intern Med, December 18, 2001; 135(12): 1061 - 1073. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. J. Soucier, S. Mirza, M. G. Abordo, E. Berns, H. C. Dalamagas, A. Hanna, and D. I. Silverman Predictors of conversion of atrial fibrillation after cardiac operation in the absence of class I or III antiarrhythmic medications Ann. Thorac. Surg., September 1, 2001; 72(3): 694 - 697. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. W. Hogue Jr and M. L. Hyder Atrial fibrillation after cardiac operation: risks, mechanisms, and treatment Ann. Thorac. Surg., January 1, 2000; 69(1): 300 - 306. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. T. VanderLugt, T. Mattioni, S. Denker, D. Torchiana, T. Ahern, L. K. Wakefield, K. T. Perry, and P. R. Kowey Efficacy and Safety of Ibutilide Fumarate for the Conversion of Atrial Arrhythmias After Cardiac Surgery Circulation, July 27, 1999; 100(4): 369 - 375. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. Reiffel Intravenous Amiodarone in the Management of Atrial Fibrillation Journal of Cardiovascular Pharmacology and Therapeutics, January 1, 1999; 4(4): 199 - 204. [Abstract] [PDF]
|
|
|
|
 |
|
 S. R. Ommen, J. A. Odell, and M. S. Stanton Atrial Arrhythmias after Cardiothoracic Surgery N. Engl. J. Med., May 15, 1997; 336(20): 1429 - 1434. [Full Text] [PDF]
|
|
|
|
 |
|
 C. Baufreton, P. Le Besnerais, P. Jansen, J. P. Mazzucotelli, C. R. Wildevuur, and D. Y Loisance Clinical outcome after coronary surgery with heparin-coated extracorporeal circuits for cardiopulmonary bypass Perfusion, November 1, 1996; 11(6): 437 - 443. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
