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European Journal of Cardio-Thoracic Surgery, Vol 8, 379-383, Copyright © 1994 by European Association for Cardio-thoracic Surgery
RC Elkins, CJ Knott-Craig, JD Randolph, JR Razook, KE Ward, ED Overholt and MM Lane
Pulmonary autograft replacement (PAG) of the aortic valve in children has
been shown to be safe and effective with a low incidence of late valve
dysfunction. Relief of all types of left ventricular outflow tract
obstruction using the pulmonary root has been possible. Concern about the
durability of the pulmonary root in the aortic position, and the potential
for growth of the pulmonary autograft used either as a root replacement or
intraaortic implant, has been questioned. Sixty- five consecutive patients,
aged 1.8 to 21 years (mean 12 years) operated on between September 1986 and
January 1993, 35 with an intra- aortic implant (IA) and 30 with root
replacement (RR), were evaluated by clinical and serial echocardiographic
studies (ECHO) up to 6.5 years post-operatively. The hospital mortality
rate was 3.0% (70% CL 2.1- 5.1%). Two patients required reoperation for PAG
insufficiency (AI), one for technical malalignment necessitating
replacement at 6 months, and one with progressive leaflet prolapse due to
adherence of the valve leaflet to a ventricular septal defect (VSD) patch.
Freedom from significant aortic regurgitation at 6-year follow-up was 100%
for RR and 91 +/- 6% for IA, and freedom from all valve-related
complications including reoperation was 92 +/- 5% at 6 years. Significant
enlargement of the aortic annulus which parallels somatic growth has been
measured by ECHO in 17 IA implants (P < 0.001) and 17 RR patients (P
< 0.01) by 1 year, and in 10 IA (P = 0.007) and 6 RR (P < 0.05) by 2
years.(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Medium-term follow-up of pulmonary autograft replacement of aortic valves in children
Dept. of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City 73190.
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