HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Townend, J. N. Articles by Bonser, R. S. Search for Related Content PubMed PubMed Citation Articles by Townend, J. N. Articles by Bonser, R. S.

European Journal of Cardio-Thoracic Surgery, Vol 9, 507-513, Copyright © 1995 by European Association for Cardio-thoracic Surgery

ARTICLES

Results of surgical revascularization in ischaemic heart failure without angina

JN Townend, D Pagano, SM Allen, P Jordan, MK Davies, WA Littler and RS Bonser
Department of Cardiothoracic Surgery, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK.

Seventeen patients with severe ischaemic heart failure without angina were studied prospectively to determine the effects of surgical revascularization on exercise tolerance, peak oxygen consumption and left ventricular function at rest and during inotropic stimulation at 3 months after surgery. Suitability for surgery was assessed by the presence of ischaemia identified by thallium scintigraphy and stress electrocardiographic (ECG) testing and the left ventricular response to dobutamine measured by radionuclide ventriculography. One patient died awaiting surgery and one required cardiac transplantation. Fifteen patients underwent coronary artery surgery with two perioperative deaths. Thirteen patients were restudied 3 months after surgery. Mean treadmill exercise time (362 +/- 204 s to 562 +/- 303 s, P < 0.05) and peak oxygen consumption (14.9 +/- 3.5 ml/kg per min to 20.8 ml/kg per min, P < 0.01) increased significantly. Resting ejection fraction was not changed after surgery (20 +/- 5% to 21 +/- 6%) but ejection fraction during derived from thermodilution Swan-Ganz catheter data both at rest during dobutamine stimulation were unchanged after surgery. At 13 +/- 3 months after surgery there had been three sudden deaths and one patient had undergone successful cardiac transplantation. Of the remaining nine patients, three had improved to NYHA symptomatic class I, three were in NYHA class II and three in NYHA class III. Repeat treadmill exercise testing in seven patients showed that the improvement in exercise capacity evident in the first follow- up visit was maintained during long-term follow-up.

This article has been cited by other articles:

				P. J. Shah, D. L. Hare, J. S. Raman, I. Gordon, R. K. Chan, J. D. Horowitz, A. Rosalion, and B. F. Buxton Survival after myocardial revascularization for ischemic cardiomyopathy: A prospective ten-year follow-up study J. Thorac. Cardiovasc. Surg., November 1, 2003; 126(5): 1320 - 1327. [Abstract] [Full Text] [PDF]

				R. Lorusso, G. La Canna, C. Ceconi, V. Borghetti, P. Totaro, G. Parrinello, G. Coletti, and G. Minzioni Long-term results of coronary artery bypass grafting procedure in the presence of left ventricular dysfunction and hibernating myocardium Eur. J. Cardiothorac. Surg., November 1, 2001; 20(5): 937 - 948. [Abstract] [Full Text] [PDF]

				G. B. Luciani, G. Montalbano, G. Casali, and A. Mazzucco Predicting long-term functional results after myocardial revascularization in ischemic cardiomyopathy J. Thorac. Cardiovasc. Surg., September 1, 2000; 120(3): 478 - 489. [Abstract] [Full Text] [PDF]

				M E Lewis, M P. Pitt, and R S Bonser Surgical alternatives to mechanical support Perfusion, July 1, 2000; 15(4): 379 - 386. [PDF]

				D Pagano, M E Lewis, J N Townend, P Davies, P G Camici, and R S Bonser Coronary revascularisation for postischaemic heart failure: how myocardial viability affects survival Heart, December 1, 1999; 82(6): 684 - 688. [Abstract] [Full Text]

				K.F. Fox, M.R. Cowie, D.A. Wood, A.J.S. Coats, P.A. Poole-Wilson, and G.C. Sutton New perspectives on heart failure due to myocardial ischaemia Eur. Heart J., February 2, 1999; 20(4): 256 - 262. [PDF]

				D. Pagano, J. N. Townend, W. A. Littler, R. Horton, P. G. Camici, and R. S. Bonser Coronary artery bypass surgery as treatment for ischemic heart failure: the predictive value of viability assessment with quantitative positron emission tomography for symptomatic and functional outcome J. Thorac. Cardiovasc. Surg., April 1, 1998; 115(4): 791 - 799. [Abstract] [Full Text] [PDF]

				G. E. Cimochowski, M. D. Harostock, and P. J. Foldes MINIMAL OPERATIVE MORTALITY IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS WITH SIGNIFICANT LEFT VENTRICULAR DYSFUNCTION BY MAXIMIZATION OF METABOLIC AND MECHANICAL SUPPORT J. Thorac. Cardiovasc. Surg., April 1, 1997; 113(4): 655 - 666. [Abstract] [Full Text]