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Eur J Cardiothorac Surg 2003;24:852
© 2003 Elsevier Science NL

Letter to the Editor

The role of early ischemic preconditioning in spinal cord protection after transient aortic occlusion

Department of Cardiac Surgery, University Hospital of Ioannina, Dourouti, Ioannina, 45110, Greece

Received 17 July 2003; accepted 10 August 2003.

^* Tel.: +30-697-724-3942; fax: +30-26510-97057
e-mail: toumpoul@otenet.gr

Key Words: Ischemic preconditioning • Spinal cord • Aortic occlusion

The first 20% of the full text of this article appears below.

I read with great interest the article titled ‘Ischemic preconditioning and nicotinamide in spinal cord protection in an experimental model of transient aortic occlusion’ [1]. I congratulate Isbir and associates on their study of ischemic preconditioning (IPC) and nicotinamide utilization to provide spinal cord protection.

IPC is a biphasic phenomenon with an early and a late phase of protection. These two phases have been documented in the spinal cord [2–4]. In this study Isbir et al. evaluated the effect of either early IPC (group 2) or nicotinamide (group 3) or combined . . . [Full Text of this Article]