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Eur J Cardiothorac Surg 2005;28:831-832
© 2005 Elsevier Science NL
Department of Surgery, Ulleval University Hospital, 0407 Oslo, Norway
(Email: i.j.vaage@medisin.uio.no).
| The first 20% of the full text of this article appears below. |
The first coronary artery bypass surgery I witnessed as a resident was with intermittent aortic cross-clamping and ventricular fibrillation and with a large vent into the left ventricular apex as myocardial protection. During subsequent years and in parallel with the advances and improvements of cardioplegia, it was always a mystery to me how good results could be reported with intermittent cross-clamping as myocardial protection. Many cardiac surgeons who are strong believers in cardioplegia as the technique of choice for myocardial protection have been surprised and puzzled by the good clinical results presented by surgeons using intermittent cross-clamping [1,2,3]. However, the present study by Fuji and Chambers [4] provides strong data to support what some of us have believed in the back of our minds that intermittent cross-clamping with ventricular fibrillation may represent a way of preconditioning the heart. The present study is an excellent research report using the classic, isolated Langendoff-perfused rat heart. It is from a research
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