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Eur J Cardiothorac Surg 2006;29:637
© 2006 Elsevier Science NL

Letter to the Editor

Comparison of mast cell properties and myocardial structure in dilated and ischemic hearts under mechanical circulatory support

Ahmet Akgul a , * , George P Noon b

a Yuksek Ihtisas Hospital, Department of Cardiovascular Surgery, Ankara, Turkey
b Michael E. DeBakey Department of Surgery, Division of Transplantation and Assist Devices, Baylor College of Medicine, Houston, TX, USA

Received 1 January 2006; accepted 16 January 2006.

* Corresponding author. Address: Mahmut Esat Bozkurt Caddesi, No: 17/7, Incesu 06600, Ankara, Turkey. Tel.: +90 312 431 45 17; fax: +90 312 431 94 13. (Email: aakgul@hotmail.com).

Key Words: Cardiomyopathy • Mast cell • Re-remodeling • Collagen • bFGF • Left ventricular assist device

The first 20% of the full text of this article appears below.

We read the excellent study of Ibaraki et al. [1] with great interest. They found that both tryptase-positive mast cells (MCT) and tryptase- and chymase-positive mast cells (MCTC) counts in the border lung cancer region, where microvessels counts higher, were higher than in the central region. The ratio of MCTC to MCT in the border region was significantly higher than that in the normal region. They concluded that MCTC might be involved in the pathogenesis of angiogenesis in lung cancer.

Although our studies were not related to lung disease, mast cells and their products in the heart remain the . . . [Full Text of this Article]






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Copyright © 2006 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.