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Eur J Cardiothorac Surg 2006;29:747
© 2006 Elsevier Science NL

Editorial comment

Differential, time-dependent effects of perivenous application of fibrin glue on medial thickening in porcine saphenous vein grafts

Montreal Heart Institute, Université de Montréal, 5000 Belanger Street, Montreal, Que., Canada H1T1C8

^_* Corresponding author. Tel.: +1 514 376 3330; fax: +1 514 376 1355. (Email: louis.perrault@icm-mhi.org).

The first 20% of the full text of this article appears below.

The study presented by Wan and co-workers explores the effect of extravascular support of venous anastomosis by perivenous injection of fibrin glue on medial thickening 1 and 4 months after intervention in a porcine model. Although this study was negative and, in fact, showed detrimental results with use of this technique, the authors should be commanded for their initiative of testing in an in vivo relevant model, a hypothesis that was raised under ex vivo nonpulsatile flow conditions. Such research initiatives are mandatory . . . [Full Text of this Article]