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Eur J Cardiothorac Surg 2006;30:817-818
© 2006 Elsevier Science NL

Letters to the Editor

Reply to Velimirovic

Helical myocardial ventricular myocardial band; cardiac resynchronization therapy

David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue 62-258 CHS, Los Angeles, CA 90095-1741, United States

Received 24 August 2006; accepted 28 August 2006.

^_* Tel.: +1 310 206 1027; fax: +1 310 825 5895. (Email: gbuckberg@mednet.ucla.edu).

Key Words: Helical ventricular myocardial band • Biventricular pacing • Structure/function relationship • Functional mitral regurgitation

The first 20% of the full text of this article appears below.

Insight into functional aspects of electrophysiology requires synthesis of form and motion during planning and enactment of pacing strategies [1]. Tomioka et al. [2] employed the helical ventricular myocardial band (HVMB) to determine if this spatial geometry model, together with prior knowledge about rapid axial and slower radial electro-physiologic conduction velocities, could explain cardiac resynchronization therapy benefits during heart failure.

A central theme is understanding how the anatomic distribution of the His Purkinje system that touches only a few millimeters of nerve myocyte connection, can effect sequential contraction following subsequent transmural impulse heart muscle transmission. Such knowledge . . . [Full Text of this Article]